SCN Mechanism of Communication - Article Example

Consequently, the authors show how circadian rhythm is produced by the donor tissue and not a consequence of spontaneous recovery of function.

The title, a diffusible coupling signal from transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms, is adequate in describing the content of the article. It contains the entire content that is discussed in the article. From the article, the authors’ goal is to show that transplanted SCN can sustain circadian activity rhythms by diffusible signal means. The fact that the transplant of SCN restored circadian activity rhythms to ablated animal SCN has motivated the research and discussion in the paper. The other factor is that the coupling nature of signals from grafted SCN is unknown and presumed that re-establishment of appropriate synaptic connection is required in functional recovery.

In conclusion, the findings showed that neural afferents are essential for circadian rhythmicity. Additionally, it shows how the circadian rhythm of SCN can be relayed to targets. Further, the results demonstrate that a diffusible signal is sufficient for rhythmicity restoration. The finding in the paper is significant as it demonstrates how the diffusible signal is sufficient in rhythmicity restoration.

How significant is a diffusible signal in suprachiasmatic nucleus transplant?

How effective is the transplanted SCN to animals whose SCN has been ablated?