Treatments for Type 1 Diabetes Mellitus - Research Paper Example

Diabetes is, at the moment, ranked as the 6th leading cause of death in the United States (Rubino et al 1). In many other states, it ranks far much higher due to their deprived status of dealing with the illness. The financial turmoil, in 2007 alone, went beyond US$ 174 billion. Oral hypoglycemic and diet modification have proven inadequate, while insulin therapy simply solves the matter temporarily. In the United States Prospective Diabetes Study, people with diabetes were treated with insulin, diet modification, sulfonylurea and metformin (Sloan 194).

At one with the progressive trait of diabetes, monotherapy was deserted in 75 percent of the diabetic patients assessed in a follow-up of 10 years. Even with the new-fangled pharmaco-therapies, diabetic patients still develop micro- and macro-vascular effects. Diabetes is connected to increased stroke- and cardiac-related deaths, blindness and kidney failure, as well as 69% of the non-trauma lower-limb amputations (Sloan 194). In cardiac surgery, the illness as a preoperative risk element confers much better morbidity than a previous myocardial infarction.

Whereas this numbers indicate to us that this disease will be a global health concern of the next generation, its actual pathophysiology is yet to be defined. Alternative treatments targeting diverse models of this disease need vigilant and responsible assessment. A tremendous body of proof now showcases that surgery for type 1 diabetes can achieve complete illness remission, an objective almost unprecedented in recent diabetes care (Perry 22; Montenero 98; Fox 1550). Data gathered over many years of surgery showcases the success and durability of diabetes management gained after the surgery.

Metabolic surgery is, at the moment, emerging as a field devoted to the development of surgical processes, particularly intended to treat diabetes. However, what about non-surgical treatment? Type 1 is treated non-surgically with insulin replacement – normally