The Importance of Bioinformatics - Annotated Bibliography Example

However, the article’s limitation is that it does not clearly distinguish the number of females and males plus kids in the study. It is noteworthy that the article first describes cancer as caused by the alteration of the proteome and the genome. These changes teach the ability to evade standard cellular control mechanisms on cancer cells, prompting their uncontrolled growth. The article further demonstrates that before the efforts of scientists, cancer was controllable to some extent or even totally if detected at its early stages. Considerably, among the several individuals who were interviewed on the same, are concluded to be ignorant. The respondents sought medical attention upon developing the disorder's symptoms. However, the limitation of the article is that it does not illustrate perfectly why patients usually seek medical help at a later stage of cancer.

The importance of bioinformatics in cancer disease is highlighted in this article. Bioinformatics is the study of predictive molecular signatures, also called biomarkers. Biomarkers are a form of molecules whose occurrence indicates the pedigree of several diseases. At this point, scientists started exploring in their quest to find a limiting factor to this terrible disease. It is imperative that the author of this article did not highlight the details of the biomarkers. Thus, the arguments are limited. The author alludes that the biomarkers have been discovered to limit the severity of the disease in the human body.

The above article states that bioinformatics has been formulated to counter it since the growth of cancer portrays a form of a multi-scale process dominated by an invariable that exudes non-linear dynamics. According to the author in the above article, some form of cancer therapy design exists, which cuts short the main components of critical pathways within the complex cancer system. In addition, bioinformatics also tries to stifle angiogenesis, a process that makes cancer suffocate due to a lack of essential substrate.

The laboratory evidence portrays the methodology in this article, where the author analysed some samples of doctors concerned about cancer. However, its limitation is that the message is not passed over in its simplicity. As well as, there was no specimen for the above confirmation in the article.

The author of this article goes into detail concerning biomarkers. It illustrates that the biomarkers attack the hubs and bottlenecks caused by cancer. However, it amplifies the dynamic protein networks after a while. These protein networks help in fighting the existence of cancer in the body. Such proteins play crucial roles in reducing cancer in the affected part of the body. Multiple oncogenes can be termed tumour-targeted by miRNAs. Other multiple oncogenes, under the influence of bioinformatics, are said to be eliminated in leukaemia.

The methodology here illustrated a study done by several doctors on cancer patients. A sample of fifty people took the participation. Its limitation was that the authors used most medical terminologies, which can easily confuse them.