Escherichia coli ESBL positive and its interaction with the human urothelial cells - Dissertation Example

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Escherichia coli ESBL positive and its interaction with the human urothelial cells

The gene encoding the antibiotic resistance is found on plasmids, transposons, and inserted in genes in bacteria all over the world and in multiple species. Although much research has been conducted to characterize the microbial enzyme biochemically, PCR analysis remains the “gold standard (4, 5, 6).” E. coli isolates from the environment are generally succeptible to beta-lactam antibiotics because of the absence of a strong promoter sequence for the expression of the gene for Beta-Lactamase. However, extensive use of antibiotics and the spread of genetic elements among the bacteria have resulted in development of Beta-lactam resistant strains. Consequently, Beta-lactam resistant strains of E. coli have been isolated from hospitals and clinics around the world (7, 8, 9). Klebsiella is a member of the Enterobacteria that is a small, non-motile rod, and the bacterium is often associated with urinary tract infections. Klebsiella is capable of nonaerobic metabolism and is found in water and soil, in addition to the mammalian intestinal and urinary tracts. ...
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ESBL positive Escherichia coli and Klebsiella interaction with human urothelial cells. Introduction The Enterobacteria constitute a group of bacteria that are small rods and can be mobile or immobile. This group is characterized by the ability to conduct facultative anaerobiosis and include Escherichia coli, Klebsiella, Salmonella, Shigella, Pasteurella, Yersinia, Enterobacter, Serratia, Proteus, Vibrio, Aeromonas, and Photobacterium…
Author : matt35

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