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At the outset the authors claim that this particular study as per their knowledge is the first to assess independent risk factors in a co-colonization scenario. Hence a lenient approach is being adopted in this critique for the simple reason that only once we have more data/publications the world over in the same area of research, can there be a concrete establishment of the actual prevalence, risk factors and clinical outcomes of patients who are co-colonized by vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA)…
Although adequate, some elaboration on the extent of the VRE and MRSA individual infections world-wide in Introduction and discussion would have achieved a better impact in the minds of the reader. Such an elaboration becomes essential taking into consideration that these kinds of publications are read not only by clinicians but also by researchers worldwide working in non-medical areas, as well.
In the aims of the study, patient-to-patient transmission, one of the major routes of nosocomial infections, was not included. This becomes vital taking into observation that some of the patients included in the study were transferred from another hospital to University of Maryland Medical Center (UMMC) [see table 1] and from UMMC to other hospitals and elsewhere. Without including this particular parameter, the authors suggest limiting of patient-to-patient transmission as a remedial measure.
In the laboratory methods, a reference to the mentioned method of culturing is missing. If the method adopted is novel, the same should have been mentioned at appropriate places. ...