Pharmacology - Lab Report Example

Only on StudentShare

Extract of sample
Pharmacology

The biochemicals that initiate such change are also known as Second Messengers.
Antagonists also bind to receptors but they do not have the ability of agonists to initiate changes in cellular functions. Instead, their prime characteristics are that they tend to occupy receptor surfaces thereby blocking agonist bindings on the same surface. This diminishes or even totally inhibits agonist functions that initiate changes in cellular functions. That is why they are termed as antagonists or blockers. There are two kinds of antagonists: competitive and irreversible. Competitive antagonists bind reversibly with receptors and high dosage of agonists may displace them and reinstate agonist interaction. On the other hand, irreversible antagonists bind irreversibly with receptors and do not allow displacement with increasing dosage of agonists. (Piascik, M.T., 2005)
In the first half of the first set of experiments acetylcholine (Ach) was used in isolation in 8 varyingly increasing concentrations to separate segments of the guinea pig ileum tissue. The response times to the dosages were noted and recorded. Ach is a known agonist and binds with receptors in smooth muscle cells to cause contraction.
In ...
Download paper

Summary

To better understand the full implications of the interpretations of the results of this practical it is first deemed necessary to define a few important concepts dealt with herein. The definitions are as below.
The ability of a drug to bind to a particular receptor on a cellular environment is determined by the chemical structure of the drug that allows it to interact with complementary surfaces on the receptor…
Author : hodkiewiczthere

Related Essays

Pharmacology
13 pages (3263 words) Essay
PHARMACOLOGY
2 pages (502 words) Essay
Pharmacology Report
4 pages (1004 words) Research Paper
Pharmacology
9 pages (2259 words) Essay
Pharmacology
4 pages (1004 words) Essay
Cancer Pharmacology
20 pages (5020 words) Essay
Got a tricky question? Receive an answer from students like you! Try us!