Betalactam Antibiotics - Essay Example

Only on StudentShare

Extract of sample
Betalactam Antibiotics

This review addresses the feasibility of utilizing members of the beta-lactam group of antibiotics in the management of tuberculosis. The first part provides an introduction into the beta-lactam antibiotics as a group, their distinguishing features, their classification, their spectrum of activity, and their mechanism of antibacterial action. Next follows a brief overview of tuberculosis as a disease which poses a peculiar challenge with drug therapy. The literature review section features an extensive overview of current research publications addressing various angles of the question of utilizing beta-lactam antibiotics in tuberculosis treatment, including results from in vitro as well as in vivo testing, clinical trials, and comments from reviewers. Finally, an appraisal of the available information is done, drawing out answers to the questions of why the beta-lactams have not been used in tuberculosis treatment, what are the issues involved, how they may be used to treat tuberculosis, what conclusions may be drawn from the literature information available, and the place of combination therapy in facilitating the utility of the beta-lactams in tuberculosis therapy.
Beta-lactam antibiotics refer to a broad class of antimicrobials ...
Download paper


Beta-lactam antibiotics are a widely utilised class of antibiotics in clinical treatment. However, they have not been associated with the treatment of tuberculosis. The reasons for this situation are examined, as well as the recent advances in research which point to the potential utility of these antibiotics in the tuberculosis treatment, especially in cases of multidrug-resistant tuberculosis…
Author : durganvito

Related Essays

The Joint Commission Approach to Quality Assurance
It has been estimated that nosocomial infections cost the country between $28 billion to $33 billion each year (AHRQ, 2009). Although there are many types of bacteria responsible for HAIs, the most common is methicillin-resistant Staphylococcus Aureus (MRSA). Studies have revealed that the number of hospital stays associated with MRSA tripled from 128,500 in 2000 to 368,600 in 2005 (Elixhauser & Steiner, 2007). Patients who contract nosocomial infections during their hospital stay have extended hospital stays and have a higher rate of death when compared to patients who do not contract these...
8 pages (2008 words) Research Paper
The Health Risks to Humans of Using Antibiotics, Steroids and Hormones in Meat Products
Further, the Food and Drug Administration is designed to be an objective research-based organization conducting its own independent studies. In nearly all instances associated with hormone and steroid use, the FDA has found little evidence to suggest human health is compromised through these practices. At the same time, health researchers conduct similarly-based studies only to conclude that there are legitimate health consequences associated with not only steroid and hormone use, but also in relation to antibiotic injection and feed practices. Depending on which entity provides the most trust...
3 pages (753 words) Research Paper
antibiotics and nephrotoxicity
Additional causes of reduced glomerular filtration can also be caused by activation of the tubuloglomerular feedback systems due to the chemical mechanisms of the drug (Lopez-Novoa et al, 2011). The main cause of these symptoms appears to be the accumulation of drugs in renal cells, resulting from an endocytic receptor complex (which has the function of transporting proteins in cells) formed from megalin and cubulin (Quiros et al, 2011). Gentamicin in particular accumulates in the endosomal compartment and the endoplasmic reticulum, causing stress and unleashing a protein response throughout...
4 pages (1004 words) Term Paper
Worldwide estimates have revealed that infections that persist due to antibiotic resistance are the second-leading cause of death. In many other cases it has resulted in increased treatment costs, hospital stay and doctor visits (U.S. Department of Health and Human Services, 2013). This development of resistance has been largely attributed to the ability of microbes to adapt and mutate in order to survive in their host organisms. While it is nearly impossible to prevent this mutating ability of microbes and hence the development of resistance to antibiotics, humans can nevertheless control the...
5 pages (1255 words) Research Paper
Contrast between vegetarians and meat eaters
In the same time meat eaters are representative of old world who don't believe in ascertained facts of e existence products what can substitute for daily requirement of the human. The human wasn't born vegetarian and didn't feed on a weed, that opinion direct me on the thinking that ration of children couldn't consist of just vegetarian foot, problem is digging much deeper without complete ration (egg, milk, meat) children lose occasion to growth health human. If you don't refuse from the fruits, vegetables, sea products, it's not mean that your food is balanced - it's wrong meaning, paying...
2 pages (502 words) Essay
Chemotherapy and Antibiotics
The paper throws light on cancer, the abnormal production of the cells of an organism which are proliferated in an uncontrolled way and sometimes spread. Cancer is commonly used for all types of malignant tumors, which is the swelling of any tissue of the body caused by inflammation, which are studied in Oncology. Neoplasm is defined by a British oncologist Willis as “Abnormal mass of tissue, the growth of which exceeds and is uncoordinated with that of the normal tissue and persists in the same excessive manner after cessation of the stimuli which evoked the change.” The types of cancer...
5 pages (1255 words) Essay
Got a tricky question? Receive an answer from students like you! Try us!