Therefore, we only develop cancer when our immune cells fail to either recognize or destroy these abnormal cells. Unfortunately, most tumor and cancerous cells show little response to the control mechanisms of the human immune system. One reason why cytotoxic T cells fail to recognize malignant cells is due to the actions mediated by the antigens on these malignant cells (Medicine Net 2011). Breakthrough in Cancer treatment: Dr. Jane They of Maastricht University states that an effective cancer treatment with gene therapy involves three aspects. Firstly, we need to identify and isolate a therapeutic gene which will show tumor regression. Secondly, the anti cancer agent used must be equipped with the ability to differentiate between cancerous and normal host cells. Last but not the least; the employed therapeutic gene must be capable of effectively locating the necrotic areas within the tumor. This is where the bacterial use for cancer treatment comes in i.e. to provide a way to deliver the therapeutic gene to the cancerous cells. (Spreen et al 2009) Over the years scientists have been continuously striving to develop a cure for cancer; from surgery, drugs and chemotherapy. However, scientists have been successful in finding an effective cure for cancer by using an innocuous soil bacterium known as Clostridium. However, the observation that bacteria can be used to target and destroy cancerous cells is not a new one, in fact the idea dates back to almost 150 years. Two German physicians W. Busch and F. Fehleisen observed cancer regression in patients who suffered from accidental erysipelas infections during the time they were hospitalized. Moreover, an American physician William Coley observed that one of his neck cancer patient started showing dramatic recovery after contracting an erysipelas infection. The discovery that bacteria can cause cancer regression motivated Coley and he dedicated his entire life to seek ways to use bacteria in cancer therapy. Unfortunately, no effective bacterial cure for cancer could be discovered which did not cause serious toxicological complications in patients. However, several years later, the interest to use bacteria for the treatment of solid tumors was re sparked. Clinical trials involving Clostridium began in the early 1960s. The pathogenic species of Clostridium are responsible for serious illnesses such as tetanus and botulism. Whereas, most Clostridium species are innocuous that thrive in anaerobic conditions. These anaerobic bacteria form highly resistant spores when exposed to oxygen rich conditions. However, the bacteria cannot grow or multiply within these highly resistant spores. Several experiments in animals revealed that preferential proliferation in necrotic areas of tumor was shown by anaerobic pathogenic species of Clostridium. Although tumor regression was observed in animals treated with clostridium but most of them developed acute toxicity and later died. Therefore, researchers decided to use non pathogenic species strains such as Clostridium M55 for the treatment of tumors. Clostridium M55 and Clostridium sporongenes are non pathogenic species which can only grow in anaerobic surroundings such as deep soils or within the necrotic regions of tumors. Therefore, an intravenous administration of
Cite this document
(“Bacterial Cure for Cancer Essay Example | Topics and Well Written Essays - 1000 words”, n.d.)
Retrieved from https://studentshare.net/health-sciences-medicine/45613-bacterial-cure-for-cancer
(Bacterial Cure for Cancer Essay Example | Topics and Well Written Essays - 1000 Words)
“Bacterial Cure for Cancer Essay Example | Topics and Well Written Essays - 1000 Words”, n.d. https://studentshare.net/health-sciences-medicine/45613-bacterial-cure-for-cancer.
Cited: 0 times
Bacterial Cure for Cancer 16-09-11 Bacterial Cure for Cancer Introduction: Today, in developing countries cancer is one of the leading causes of death. The incidence of cancer as a cause of death is rapidly increasing. Cancer cells originate due to mutation of a host cell in response to chemical carcinogens, viruses or radiation…
Breast Cancer, Is There A Cure? Cherry Hilliard Biology 210-07 Breast cancer, is there a cure? Breast cancer is one of the growing diseases among women all over the world. A lot of cures have been identified for the breast cancer in the recent years. Some of them have their side-effects, which in some cases are manageable and in other cases, are not.
Cancer Name of the Student Creative Writing Name of the Concerned Professor May 13, 2012 Cancer There is no denying the fact that cancer is a disease that commands loads of shock, fear and stress in the popular perception. Strictly speaking, cancer is not a new disease.
Jones et al (2000, p. 1026) explain that some micro-organisms are said to be opportunistic since they cannot infect a person under normal circumstances, but are found to take advantage and cause disease when the immune system of the body is impaired. Thus, opportunistic infection is seen to manifest itself only when a person is ill and the body defense mechanisms are affected.
Cells are naturally designed to multiply in a controllable manner, failure to which a cancer may develop. The uncontrolled cell multiplication can be attributed to mutation of genes (a molecular unit in our DNA, which contains information of how cells operate).
The researcher analyzed Intake of Dairy Products, Calcium, and Vitamin D and Risk of Breast Cancer study by Shin, Holmes, Dietary Intake of Conjugated Linoleic Acids and Risk of Premenopausal and Postmenopausal Breast Cancer, Western New York Exposures and Breast Cancer Study and a few more studies on the subject.
The treatment of some type of cancer, for example prostate caner usually goes on for many months. After treatment, the surviving patients usually require intensive care from medical specialists so that they can manage their
Cancer has been a part of the human condition since recorded history. The earliest evidence of cancer is found among fossilized bone tumors, human mummies and manuscripts in ancient Egypt, dating to about 3000 B.C. The cause of cancer was variously attributed to the Gods,