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Rapid Measurement of B-Type Natriuretic Peptide - Article Example

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Rapid Measurement of B-Type Natriuretic Peptide

Yes and yes. With proper and quick diagnosis proper interventions can be applied. Patients suffering from dyspnea can be screened for congestive failure of the heart, and cardiac interventions can be rapidly undertaken if the peptide measurement tests establish such. The rapid nature of the measurement and the rapid ability to generate results/diagnoses is of importance in patients suffering from heart failure, because the time from heart failure to brain death is very short, and there is only a short window of time wherein heart failure victims can be rescued from death (Maisel et al.)2. Test availabilityIn hospital and ER settings the bedside assay can be made standard, and the laboratory can make testing for peptide levels a standard procedure as well (Maisel et al)3. Would the information change congestive heart failure diagnosis in 2012If true, the information can be helpful and can change diagnosis protocols, to include rapid peptide level measurements. Such measurements can complement standard diagnostic procedures and clinical tests for the establishment of the congestive heart failure, as the study suggests (Maisel et al.)SECTION V- Validity1. Addressed DiseaseCongestive heart failure with dyspnea as the most visible symptom (Maisel et al.)2. Diagnostic test evaluatedMeasurement of levels of B-type natriuretic peptide levels in emergency room patients presented with dyspnea, via bedside assay (Maisel et al.)...
On their own, the measurements of the B-type natriuretic peptides had a greater level of accuracy with regard to determining dyspnea as being caused by the congestive failure of the heart. This is in comparison to other means of determination, to lab values, historical findings, or even physical findings. At a 100 pg per mL cutoff, the accuracy of diagnosis of B-type natriuretic peptide measurements was pegged at 83.4 percent. 96 percent negative predictive value was observed for levels of the peptide of lower than 50 pg per mL. In statistical analyses, such B-type natriuretic peptide measurements, on their own, was an addition to the strength of power of prediction with regard to pinpointing which patients had congestive failure of the heart, complementing a slew of other commonly used clinical variables for such predictions. This is true for such statistical tests as multiple logistic regression, to which the peptide measurements lend themselves to being a strong predictor of the presence of congestive heart failure in patients measured for the peptide levels (Maisel et al. 161). 2. Clinical Question Is the quick measurement of the levels of B-type natriuretic peptide in patients with dyspnea a good predictor of the presence or absence of congestive failure of the heart in such patients, and at what levels of do such measurements have strong predictive power? (Maisel et al.) SECTION II - Background 1. Purpose of the Research To determine the predictive power of measured B-type natriuretic peptide levels in patients with dyspnea, where measurements are taken concomittant to patient admission in the emergency room, and where the diagnosis is dyspnea. (Maisel et al.) 2. Study Design The study is prospective, which means ...Show more
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The paper “Rapid Measurement of B-Type Natriuretic Peptide” aims to determine the predictive power of measured B-type natriuretic peptide levels in patients with dyspnea, where measurements are taken concomittant to patient admission in the emergency room…
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