DNA as we know tells us about our family structure and passes on from one generation to another. The large number of cells and their network helps in differentiating the DNA structure. The DNA keeps of replicating with the help of template polymerization. The Eukaryotic and Prokaryotic cells are made up of similar basic chemicals like carbohydrates, proteins, nucleic acid, minerals, fats and vitamins, while making use of proteins as catalysts. The hereditary information is transformed into RNA, which in turn is translated into proteins. Therefore these two cells are similar in nature in many respects.
But, there are a number of features which differentiate these two types cells from each other. One of the major distinctive feature is that the Prokaryote is without a nucleus, therefore the DNA keeps floating around in an unorganized manner in the cells. But on the other hand, the Eukaryote cells have a large centrally located nucleus, surrounded by double layer of membrane known as nuclear envelope. This envelope contains nucleoplasm. The DNA is held within this nucleus only. The nucleus being the centre of activities is also termed as brain of the cell. Prokaryotic cells do not have the organelles, but Eukaryotic cells have organelles which allow them to perform more complex functions.
Both these cells differ in respect of their size as well.