Critical Evaluation of the Use of Indirect Immunocytochemical Techniques in Diagnostic Pathology

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Immunocytological techniques as applied to immunohistochemistry (IHC) is an integral technique in present-day diagnostic pathology. This technique allows one to examine cytological details and tissue architecture better…

Introduction

Immunohistochemistry is a novel approach to use a natural reaction between two macromolecules, an antigen and an antibody, outside the body to make a unique pathologic diagnostic tool for present-day medicine. Labeling with colloidal gold particles that may be used in different particle sizes to carry out multiple staining at the electron microscope label, most easily by direct labeling of several first layer antibodies. ...
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