StudentShare solutions
Triangle menu

The measurement of inflammatory oedema in skin - Essay Example

Not dowloaded yet

Extract of sample
The measurement of inflammatory oedema in skin

The PubMed database contains more than 80,000 references related to the problem of the inflammation in medicine and biology. Nevertheless, the studies dedicated to the problem of inflammatory response do not loose their pertinence and keep top positions on the ranking of the most important scientific directions.
The physiology of inflammation is very complicate. There are five universal hallmarks of the inflammation, four of theme were described by Celsus in the Ancient Rome as follows tetrad: rubor (i.e. hyperemia or redness due to increased blood flow), calor (heat due to increased metabolic activity and blood flow), tumor (i.e. swelling or oedema), and dolor (i.e. pain). The fifth hallmark of the inflammation was added to the previous by Dr. Rudolf Virhow only in the middle of XIX century. This is "functio laesa" or loss of function. But these visible indices of the inflammation are the result of the sophisticated processes mediated by the numerous humoral and cellular factors (Ley, 2001).
Thus there is well known, that the inflammatory response has two components - cellular and exudative. The exudation is characterized by producing exudates i.e. fluids and cellular substances that are slowly discharged from blood vessels of inflamed tissues. The exudates contain proteins (fibrin and others) and could be released due to the increase of capillary permeability in the affected tissue. This process leads to the occurrence of oedema, thus by the measurement of swelling area the researcher can control the intensity of the inflammation. There is also important to remember that oedema distends the tissues, irritate the nervous receptors and can cause pain (Ley, 2001).
The cellular component of the inflammation is presented by the emigration of leucocytes from the blood vessels into the inflamed tissues. Nevertheless for the research planned and conducted by the schedule of our training there is more important to recognise main mediators of the inflammation.
There was demonstrated in the studies conducted recently (Ley, 2001; Sigal, 2005; Hildebrand, Pape & Krettek, 2005) that cytokines interleukin-1 and tumor necrotizing factors can play important role in the upregulation of the endothelial receptors and the processes of extravasation (i.e. e,igration of inflammatory cells into extravascular sites). This can increase intensity of swelling also.
The vasoactive agents can influence on the processes of the exudation and extravasation significantly. Nevertheless they role are not studied completely. In the last decades the researchers pais great attention to the mechanisms of the impact of some vasoactive peptides on the microvascular responses during the acute and chronic inflammation. There are many candidates for profound studies in this area, nevertheless, some investigators prefer to use calcitonin gene-related peptide (CGRP) for modelling physiological reactions during the inflammatory response. This is a 37 amino acid peptide that is produced in the central and peripheral nervous system in the rodents (rats and mice). Since 1985 (Brain et al) there is known that CGRP is an extremely potent and long lasting microvascular vasodilator which can act to potentiate ...Show more

Summary

The thesaurus of Medical Subject Headings determines the inflammation as "a pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions" (2006). Since Galen's time this phenomenon attracts the attention of physicians and scientists…
Author : dratke
The measurement of inflammatory oedema in skin essay example
Read Text Preview
Save Your Time for More Important Things
Let us write or edit the essay on your topic
"The measurement of inflammatory oedema in skin"
with a personal 20% discount.
Grab the best paper

Related Essays

Measurement
Measurement can be considered to be one of the world’s more practical discoveries and is present in almost everything that individuals involve themselves in (Emerson 46). It also plays a large role in various industries and is an essential part of the calculations that take place in their activities.
4 pages (1000 words) Essay
Skin Cancer
The outer layers of the skin are called the epidermis and are comprised of three types of cells, basal cells, squamous cells, and melanocyte cells. Cancer can occur in any of these types of cells, but the most serious occurrences are in the melanocyte cells.
2 pages (500 words) Essay
Skin Deep
Science and technology have not only made the gendered work less cumbersome, but they have also helped women retain their beauty, despite the normal life processes of work, child-birth, aging, menopause and so on. However, one does tend to wonder, sometimes, if woman emancipation has indeed liberated them truly How confident are women about their bodies, about their beliefs and their contribution to the society
3 pages (750 words) Essay
Non-Steroidal Anti-Inflammatory Drugs
Introduction [...] Non – Steroidal Anti-Inflammatory Drugs (NSAIDs) [...] is the most widely used pain [...] reliever nowadays NSAID are drugs used [...] to reduce pain fever and inflammation [...] It is called non steroidal to [...] distinguish it from steroids which have [...] a similar eicosanoid-depressing anti-inflammatory action NSAIDS [...] are unusual in that they are [...] non-narcotic NSAIDs are sometimes also referred [...] to as non-steroidal anti-inflammatory agents/analgesics (NSAIAs) [...]
2 pages (500 words) Essay
Skin Morbidity
In dermatology, the classification of populations is normally based on external skin color, on the assumption that skin structure and function are similar across different ethnic groups. But data from dermatology clinics show that the range and type of skin
2 pages (500 words) Essay
Measurement
This paper focuses on use of measurements by humans. The paper will discuss history of measuring systems, who invented them, and their importance to engineering and construction. Additionally, how
2 pages (500 words) Essay
Skin Cancer
Skin cancer is a health problem that is prevalent in society; however, the community has very limited knowledge on the matter. Many individuals have received education related to the dangers of skin cancer,
2 pages (500 words) Essay
Skin cancer
Skin cancer remains one of the most common types of cancers and involves unrolled growth of the skin cells. Statistics prove that within the past three decades more incidences of skin cancer have been diagnosed as
1 pages (250 words) Essay
Inflammatory Bowel Disease
Furthermore, I will explain which if the two diseases is more complicated. To start with, ulcerative colitis and Crohn’s illnesses tend to display similar
2 pages (500 words) Essay
Skin
During the trip, she had significant solar exposure although she wore sunscreen. Psoriasis is a complex chronic inflammatory disease that
4 pages (1000 words) Essay
Get a custom paper written
by a pro under your requirements!
Win a special DISCOUNT!
Put in your e-mail and click the button with your lucky finger
Your email
YOUR PRIZE:
Apply my DISCOUNT
Comments (0)
Rate this paper:
Thank you! Your comment has been sent and will be posted after moderation