Got a tricky question? Receive an answer from students like you! Try us!

Hyperthyroidism - Essay Example

Only on StudentShare
Author : dpacocha

Summary

Hyperthyroidism refers to any condition in which there is too much thyroid hormone in the body due to an overactive thyroid gland (American Thyroid Association 2005a). There are several possible options for treating hyperthyroidism. These include antithyroid drugs, beta blockers, radioactive iodine, iodides, and surgery (Reid & Wheeler 2005a)…

Extract of sample
Hyperthyroidism


In the US, two antithyroid medications are being used, propylthiouracil (PTU) and methimazole, while in Europe and Asia, carbimazole which has a similar action to methimazole, is being used (Fenton 2006a). Carbimazole is converted to methimazole inside the body (Ross 2008a). The three antithyroid medications mentioned belong to the class of compounds known as thionamides and these medications inhibit thyroid hormone biosynthesis by decreasing the oxidation of iodide and iodination of tyrosine (Fenton 2006b). PTU also blocks the conversion of T4 (thyroxine) hormone to the more metabolically active T3 (triiodothyronine) hormone (MedicineNet 2005a).
The chemical IUPAC name of methimazole is 1-methyl-3H-imidazole-2-thione, its chemical formula is C4H6N2S, its average molecular weight is 114.1688 g/mol, its melting point is 146 degrees Celsius, its experimental water solubility is 275g/L, and it has a half life of five to six hours (DrugBank 2007a). The following statements describe the mechanism of action of methimazole:
'Methimazole binds to thyroid peroxidase and thereby inhibits the conversion of iodide to iodine. Thyroid peroxidase normally converts iodide to iodine (via hydrogen peroxide as a cofactor) and also catalyzes the incorporation of the resulting iodide molecule onto both the three and/or five positions of the phenol rings of tyrosines found in thyroglobulin. ...
Download paper

Related Essays

Having a Baby
Kathee's problems began with the anxiety of conception. The couple made numerous attempts at the old fashioned way. They tried timing the female cycle to no avail. They used a method called the lunar cycle that insists the woman is more fertile during the same lunar phase as her birth. In desperation they experimented with different positions that they had read about on the Internet. With no pregnancy they turned to the medical community for help. Acupuncture was inexpensive and painless but did not produce any results. A similar disappointment resulted from herbal aroma therapy. Kathee even…
3 pages (753 words)
Qualities of an Effective Principal.
One thing about a principal is that he can not be a specialist in every subject, but he should provide the students with a broader curriculum which will enhance their knowledge. …
2 pages (502 words)
essay
Creativity can only be hindered if the creative person thinks he is being led into hindrance. Since he is a creative person, he must understand that the rules of decision making and problem solving are there to assist his creative abilities and not to take anything away from his self belief and creativity. If the energies are exerted in a positive manner, then there is no shadow of a doubt that these decision making and problem solving approaches would work to the advantage of the creative process which is all about understanding and comprehension of a subject or matter. The out of the box…
4 pages (1004 words)
Hyperthyroidism
any causes which include over activity of the thyroid gland as in Grave’s disease or due to neoplasias of the thyroid gland which include adenomas and carcinomas. It can also occur due to an adenoma in the anterior pituitary which leads to increased secretion of TSH which results in overstimulation of the thyroid gland and hence increased release of the thyroid hormone. Inflammation of the thyroid gland can also result in hyperthyroidism.…
essay
key mind behind the strategy of selling the products directly to the end customers which had helped the company to achieve daunting success even being a new entrant to the industry.…
1 pages (251 words)
essay
The advent of email has greatly shortened means of communication, allowing people to remain in contact with each other for virtually no cost over extended differences.…
2 pages (502 words)
essay
Courage is one thing that each and every one of us wants to have. It is an attribute of good character of bravery that make us respectable and worthy of our surroundings or the society. We can see from the fairy tale, bible stories where David killed Goliath shows how self sacrifice and bravery which comes with courage leads to heroic endings.…
5 pages (1255 words)