Asthma and nitric oxide

College
Essay
Miscellaneous
Pages 7 (1757 words)
Download 0
Nitric oxide (NO), once generally viewed only as hazardous to humans, has now become new promising means of identifying and treating respiratory diseases such as asthma. Several studies have indicated the usefulness of nitric oxide monitoring in managing asthmatic patients particularly children…

Introduction


The European Respiratory Society has indicated its conviction in the method that it has already published guidelines to standardize analysis, diagnosis and reference levels in using nitric oxide as part of respiratory treatment (Buchwald, 2005). In the United States alone, 6% those aged below 12 have been diagnosed with asthma and as high as 40% in urban areas. This reflects a 75% from data gather in the 1980's a trend that is reflected globally (World Health Organization [WHO], 2005).
Nitric oxide is a highly reactive, prevalent gas in human chemical activity. It can be found in neurons as n NOS or NOS1, in macrophages as iNOS or NOS-2, and in endothelial cells as eNOS or NOS-3 (Bor-Kucukatay, 2005). Nitric oxide is cellularly synthesized by the enzyme nitric oxide sythases denoted by NOS from arginine, molecular oxygen and NADPH. Nitric oxide interacts rapidly molecularly and disperses through cell membranes acting in a paracinic or autocrinic behavior1.
Endogenous nitric oxide is a product of L-argining amino acid and NOS. All three isofrms, NOS or NOS1, iNOS or NOS-2, eNOS or NOS-3 are found in the respiratory tract functioning a part in vascular and airway smooth muscle tone, inflammatory respiratory response, ciliary action and in eliminating bacteria, viruses and mycobacteria in the respiratory tracts (Smith et al, 2004).
Through connecting throu ...
Download paper
Not exactly what you need?

Related papers

Investigations in Asthma
This group also shows a decrease in the lifetime prevalence of asthma. In adults however, the lifetime prevalence has increased with one person in every nine being diagnosed with asthma.( Simpson & Shiekh 2010). These figures show that asthma is one of the major health problems we face today.…
Asthma and nitric oxide
The European Respiratory Society has indicated its conviction in the method that it has already published guidelines to standardize analysis, diagnosis and reference levels in using nitric oxide as part of respiratory treatment (Buchwald, 2005). In the United States alone, 6% those aged below 12 have been diagnosed with asthma and as high as 40% in urban areas. This reflects a 75% from data gather…
Occupational Asthma
OA is a disease characterized by variable obstruction of airflow and/or airway hyperresponsiveness attributable to factors associated with the workplace rather than to stimuli found outside that environment. (Nicholson, 2002)…
Asthma Essay
In spite if its prevalence, medical professionals develop dissimilar definitions of asthma. Health care authorities have quire broad definition that takes into account different factors. For instance, the National Heart, Lung and Blood Institute defines the ailment as: "a chronic inflammatory disorder of the airways (which causes recurrent episodes of wheezing, breathlessness, chest tightness and…
Diploma Paper on Asthma
In my practice, however, I have seen some patients who are in such a phase that the patient experiences some degrees of airways obstruction daily.…
Ethylene Oxide is a Carcinogen
Ethylene oxide causes leukemia, lymphoma, brain, hematopoietic and breast cancer. It is classified as carcinogenic to humans by the International Agency for Research on Cancer.(14)…
Development of a Mathematical Model
Major immediate concerns are the possibility of underground movement of the gasoline, pollution of ground water and sewage systems and contamination of housing by toxic and flammable fumes.…