The prevalence rates are quite similar throughout the world with the United States leading in the number of incidences and China showing the least. Historically, Eastern Europe and the Far East have had low rates of breast cancer which however, have begun to rise rapidly (Babb et al, 2001).
The age related incidence is also very significant in this disease as, the age group most at risk are women over 50 years old (80% of cases) and the highest number of cases is in this 50-69 age group (Office for National Statistics, London, 2008).
The treatment for breast cancer is dependent on various factors like, the type of breast cancer, the size and histopathology of the tumor, the stage of the disease and the presence or absence of certain biomarkers. The general health of the patient is also a major factor in determining the mode of treatment. The options range from unilateral to bilateral mastectomies, lumpectomy, with additional chemotherapy or radiation therapy or chemotherapy and radiation on their own. Tamoxifen, an endocrine targeting drug which acts by interfering with the activity of estrogen, a female hormone is the largest selling drug for breast cancer. ...Show more