It is unfortunate and alarming that overuse and misuse of antibiotics is bringing resistance to most of the common bacteria. The misuse of antibiotics stems primarily from the inherent inclination of doctors towards prescribing the latest and potent antibiotics without thorough microbiological, M, C & S examinations. To curb this antibiotic abuse the empirical antibiotic management has become the prime necessity of all hospitals (Hedrick, E).
Modification in the treatment is made depending upon the patient's progress and bacterial sensitivities. Antibiotic course is started before the availability of microbiological results based on common conditions, but modifications or changes are made when microbiology results are available. As:
Recommendations for initiating Antibiotic therapy: The severity of the condition, possible infecting pathogen(s) and route of administration (preferably oral) are to be considered. Constant monitor of the patient's response and changing the route of drug from IV to OD is essential within 24 hrs. Obvious advantages of OD over IV for ciprofloxacin, metronidazole and co-amoxiclav.