Got a tricky question? Receive an answer from students like you! Try us!

Research proposal in Systems Biology - Essay Example

Only on StudentShare
College
Author : magdalen02
Essay
Miscellaneous
Pages 2 (502 words)

Summary

The scientific exploration of quantitative cell simulations should enable a broader understanding of biological pathways. The use of quantitative synthetic cell simulations of cellular genes and proteins has, in recent times, proven especially elucidative on the hitherto complicated mechanism of biological pathways…

Extract of sample
Research proposal in Systems Biology

For instance, "power techniques like RNAi for the first time enables a very precise perturbation of parts of biological pathways," (Goldbeter, 2002) and development in fluorescent techniques offers us for the first time the possibility to measure mobility of single molecule in a living system and the distances and interaction of protein in vivo or calcium concentration in Cytoplasm or organelles (Goldbeter).
It is no longer news that reconstructing genetic circuits into synthetic replicas may afford unique insight into the underlying mechanism of the circuits, and that, consequent on this synthetizaton, the possibility now exists to study circuits' mechanism without impairing cellular functions. However, such insights into underlying mechanisms cannot explain why certain kinds of biological behavior can occur only under certain sets of precise conditions, and why extrapolative and intuitive expectations based upon very exact (non-quantitative) descriptions do not suffice to accurately predict such conditional behaviors.
For instance, cytosolic Ca2+ oscillations of the cellular rhythms [2,3] category "are triggered in various types of cell by treatment with a hormone or neurotransmitter." (Science Week, 1997) contrary to speculative expectations of such outcomes as dissimilar, perhaps ...
Download paper

Related Essays

Biology Research
This is due to the light reaction of photosynthesis, which splits the water molecule and releases the oxygen in the process.…
2 pages (502 words)
proposal Research Proposal
(d) Inelastic seismic design coefficients such as; structural ductility factor (), ductility reduction factor (R), structural over-strength factor () and their distributions using nonlinear static procedure, namely push-over analysis.…
10 pages (2510 words)
Research Proposal Research Proposal
In the wake of these corporate failures, basic principles and rules are being reviewed and strengthened in order to reinstall investor confidence. At the heart of these corporate governance reforms is the common interest in the effectiveness of boards of directors. Corporate governance codes, experts and activists have long advocated changes in the board structure. As a result of the successful implementation of corporate practice codes in the private sector corporations, the government has decided to implement the system in public/civil departments and government offices. The public offices…
10 pages (2510 words)
Research paper Research Proposal
Kristin Stanberry and Lee Swanson.What the Science Says: Effective Reading Interventions for Kids with Learning Disabilities.January 18, 2008. Great Schools. March 24, 2008.
Biology Research
Basal like tumors are most commonly found in Nigeria and Senegal. Research is on to find drugs to block the specific molecules that these tumors need to grow. Women with mutations in a gene called Brca1 tend to develop this kind of aggressive breast tumor. Patterns of genetic activity of these tumors are measured through special tests because what the biological tests reveal turn out to be quite different from what the human eyes perceive. Researchers used new techniques of molecular biology to determine the patterns of gene activity in the cancer cells and then to classify and sort the…
6 pages (1506 words)