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Hypersensitivity is used to describe the adverse reactions of the immune system to different allergens or substances. It is an abnormal condition typified by an overstressed and inapproporiate response of the immunse system to a second exposure to antigen or allergen (Allen et al., 2002; Holmes, 2003)…
On the other hand, simple organic substances are more commonly known to cause delayed reactions. An individual may be exposed to these allergens through inhalation, ingestion, injection, or skin contact. (Porth, 2002)
The classifications of hypersensitivity are not dependent on severity, but the type of cells, and location of tissues that is affected. Hypersensitivity reactions are classified into four types: type I (mediated by IgE), type II (tissue-specific), type III (immune-complex mediated), and type IV (cell-mediated) (Holmes, 2003). The first three types are mediated by antibodies, and the fourth type is mediated by T-cells, which produce a delayed reaction or onset of symptoms. However, it is seldom that one type occurs in isolation from the other (Nowak & Handford, 2004).
During a hypersensitivity reaction or allergic reaction, an individual is usually prescribed with bronchodilators, steroids, and antihistamines. This paper will discuss type I hypersensitivity or anaphylactic hypersensitivity, as well as the pharmacokinetics and pharmacodynamics of the three agents mentioned above. In addition, Chinese herbal medicines will also be briefly discussed.
This type describes the allergy as the immediate hypersensitivty or anaphylactic hypersensit ...
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