Down syndrome Research Paper

Research Paper
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Charles Darwin, a famous evolutionist, Arthur Miller, a famous American playright, Eva Longoria, a well-known actress and Jamie Foxx, a hip-hop artist. All of them come from different backgrounds and fields of interest but there is one thing that ties them all together: Down syndrome.


Currently, there are more than 400,000 people living with Down syndrome in the United States alone. An estimated 3-4 million people are living with Down syndrome worldwide. As global healthcare improves, the population of people with Down syndrome may double over the next 30 years (Down Syndrome Education International, 2009).
Down syndrome was first described by John Langdon Down, an English physician, when he recognized the cluster of traits common in people and published his findings in 1866. In 1959 Dr. Jeremy Lejeune discovered the fact that all people with this syndrome had an extra 21st chromosome. Down syndrome is defined medically as a genetic condition in which a person has exhibits an extra chromosome, having 37 instead of the normal 36 chromosomes. Chromosomes are rod-like structures located inside the nucleus of our cells which carry all the genetic information responsible for all our inherited characteristics. Normally, each cell contains 23 pairs of chromosomes, half of which are inherited from each parent. Down syndrome occurs when some or all of a person's cells have an extra full or partial copy of chromosome 21 (National Down Syndrome Society, 2009). There are three types of Down syndrome: nondisjunction, translocation, and mosaicism. The most common of these three, occuring in about 95% of all
cases is nondisjuntion, often referred to as Trisomy 21. ...
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