Adrenal glands, responsible for the freight, flight and fight mechanisms of the body, secrete the hormone cortisol. Increased levels of cortisol have been found in flight and fight processes. In a normal person, normal cortisol secretion helps in various body metabolisms including insulin regulation, blood pressure normalization, immunity and inflammatory conditions. However, in cases of depression, cortisol has been found to be at higher levels, impairing thyroid functions, loss of memory, fluctuation of blood sugar and pressure levels, loss of weight and weakening of muscle tissue, lower immunity, increase in abdominal fat and cholesterol levels (Heina et al, 2002).
In total, abnormal cortisol found in depression directly impacts thyroid functioning which in turn acts on all other body mechanisms impacting mental and physical wellbeing. Prolonged exposure to stress conditions results in depression, which, in turn, disturbs the neuroendocrine functions. Lack of appropriate interventions to address or cope with stress will further lower one’s self-confidence and controlling power. All these psychological impressions are a result of serotonin inhibition caused due to increased circulation of cortisol (Tafet et al, 2001). Hence, stress conditions have to be timely diagnosed and appropriate management has to be employed in order to reverse the effects of increased