StudentShare solutions
Triangle menu
  • Home
  • Subjects
  • Miscellaneous
  • Discuss the role of the laboratory in the diagnosis, classification and monitoring of the Myelodysplastic syndromes

Discuss the role of the laboratory in the diagnosis, classification and monitoring of the Myelodysplastic syndromes - Essay Example

Extract of sample
Discuss the role of the laboratory in the diagnosis, classification and monitoring of the Myelodysplastic syndromes

The main pathophysiology in this condition is that the hematopoietic stem cells do not mature in a proper fashion to healthy erythrocytes, leukocytes and platelets resulting in low counts of mature cells and abnormal morphology. Thus there are many immature cells which do not function in a proper manner leading to several complications.
MDS an be primary or secondary. Secondary MDS can occur due to several causes like exposure to radiotherapy or cytotoxic chemotherapy for another cancer, intensive pretreatment for patients with autologous bone marrow transplants, viral infection, genetic predisposition or exposure to chemicals like benzene (Emmanuel and Woermann, 2009, Nguyen, 2009). Exposure to heavy metals like lead and mercury can also result in this condition (National Cancer Institute, 2010).
80-90 percent of cases occur in those who are above 60 years of age (American Cancer Society, 2010). The incidence is men in at least 2 times more than in women (Emmanuel and Woermann, 2009). The condition is found worldwide and affects all races and ethnic groups (Emmanuel and Woermann, 2009).
The condition is associated with significant morbidity and mortality. More than 30 percent cases of MDS transform in acute leukemia (National Cancer Institute, 2010). Survival following the diagnosis of MDS is variable and dependent on the prognostic factors (Stone, 2009). The survival can occur from months to years (National Cancer Institute, 2010). In children, the course of the disease is more aggressive and the mean survival is less than 10 months (Tilak et al, 2008).
In many patients, MDS is often detected late due to absence of early symptoms. In some others, routine hematological examination may reveal the condition. Those who have advanced disease present with signs and symptoms related to the cytopenias like shortness of breath, pallor, easy fatigability, easy bruising, uncontrollable bleeding, frequent petechiae, fever and frequent infections (National Cancer ...Show more

Summary

Myelodysplastic syndrome or MDS is a heterogenous group of clonal hematopoietic disorders characterized by "a hypercellular or hypocellular marrow with impaired morphology and maturation (dysmyelopoiesis) and peripheral blood cytopenias, resulting from ineffective blood cell…
Author : yfeeney
Discuss the role of the laboratory in the diagnosis, classification and monitoring of the Myelodysplastic syndromes essay example
Read Text Preview
Save Your Time for More Important Things
Let us write or edit the essay on your topic
"Discuss the role of the laboratory in the diagnosis, classification and monitoring of the Myelodysplastic syndromes"
with a personal 20% discount.
Grab the best paper

Check these samples - they also fit your topic

Androgen Resistance Syndromes
Androgen Resistance Syndromes. Clinical syndrome of resistance to androgens (the male hormone) in human beings has been recorded for more than two hundred years. The symptom includes female appearance with both vagina and testes but without uterus, fallopian tubes or ovaries (Definition of Androgen 2011).
14 pages (3500 words) Essay
Virtual Laboratory
Many biotechnological experiments can be easily performed and explained using virtual laboratories in an effective manner. With the arrival of internet and computer technology in modern education, limitations like distance and costly instruments are no more a hurdle.
3 pages (750 words) Essay
Cellular pathology: Discuss the role of the histopathology laboratory in predicting the response of patients' tumours to thera
Traditional chemotherapeutic sessions were nonspecific and would be administered to patients regardless of their molecular history. This caused unnecessary harm and led to remission of the disease. However, advancements in histopathology have led to a practice known as molecular profiling.
4 pages (1000 words) Essay
Discuss the role of histopathology in the diagnosis and prognosis of adenocarcinoma of the colon
It is also known as large intestines. Normal colonic glands are simple and tubular, and they possess mucus secreting goblet cells. These tissues also are made up of cells that absorb water from the fecal matter back into the blood and mucus into the lumen of the colon so as to lubricate the fecal matter.
10 pages (2500 words) Essay
Clinical and Laboratory Diagnosis of Salmonellosis
Laboratory Manual and Workbook in Microbiology Applications to Patient Care). Symptoms of Salmonellosis involve: diarrhea, headache, malaise, nausea, vomiting and gastroenteritis. Incubation period of 1-3 days and duration of illness 4-7 days (Josephine A.
4 pages (1000 words) Essay
Laboratory Medecine
(This line is important to show that you have some knowledge of the field - it cannot get simpler) In simpler words, the duties and responsibilities of a medical laboratory technician revolve around the collection and categorization of blood samples into types and groups.
3 pages (750 words) Essay
Case Study Discuss the pathpyysiology of Myelofibrosis
The initiating pathologic event takes place in the bone marrow that displays features of dysplastic megakaryocyte hyperplasia, proliferation of granulocytic cell lineage, and reticulin and/or collagen fibrosis. The disease presentation clinically happens in one of the three ways, de novo, as primary myelofibrosis (PMF) or preceded by polycythemia vera known as post polycythemia vera (post-PV MF) or heralded by essential thromocythemia (Post-ET MF).
16 pages (4000 words) Essay
The laboratory diagnosis, monitoring and management of the diabetic patient
In addition, Diabetes is caused either by lack of insulin or because of the availability of factors that oppose the functionality of insulin.
9 pages (2250 words) Essay
Discuss the Standard industrial classification
However, the codes were modified in 1992 to six-digit to group industries on a broader classification platform. The first two digits of the code tell about the major group, and the three first digits of the SIC code indicates about
2 pages (500 words) Essay
Monitoring
If the employer does not communicate such policies to the employee, then they have no right to monitor the internet usage of the employees. However, in most states, employers do not have an
1 pages (250 words) Essay
Hire a pro to write
a paper under your requirements!
Win a special DISCOUNT!
Put in your e-mail and click the button with your lucky finger
Your email
YOUR PRIZE:
Apply my DISCOUNT
Comments (0)
Click to create a comment