Risk Factors for Colon Cancer - Research Paper Example

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Risk Factors for Colon Cancer

In most cases a combination of inhibitors is necessary to maximize the efficacy of the drug treatment. The possible side-effects associated with these drugs is still under investigation. Thus at present the prognosis for colon cancer associated with obesity has been found to be poor, however the combinational use of inhibitors could change the current prognosis. Keywords: colon cancer, obesity, insulin, adipokines According to recent surveys colon cancer is the third most commonly occurring cancer in males and second in the case of females associated with a mortality rate of 608,700 (Chen, 2012). About 1.2 million people are diagnosed with this type of cancer every year (Whitlock, Gill, Birch, & Karmali, 2012). There are many causative factors involved in the pathogenesis of colon cancer which include environmental factors such as a high-fat/ low-fiber dietary intake, genetic factors such as inherited or cellular genetic mutations, life style changes such as smoking, physical inactivity and obesity (Chen, 2012; Ma, Yang, Wang, Zhang, Shi, Zou, & Qin, 2013). Studies have shown a strong link between obesity and the incidence of colon cancer. Obesity, which is measured as the body mass index, is on a rise over the past few decades all over the world. ...
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Obesity and Colon cancer Your name Institute Abstract Colon cancer is the third most common type of cancer according to worldwide estimates. There are several identified risk factors for colon cancer including environmental and genetic factors. Obesity which is defined as the body mass index and is considered as a major health problem worldwide is associated with increased risk of colon cancer…
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