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NSB025 Nursing Practice in Context 5 INTRODUCTION Colorectal cancer is caused by an abnormal separation of cells in the colon of a human being (Radtke, 2005). Due to the level of damage caused by this disease, both healthy and persons with the symptoms, require regular screening.
He therefore has to be educated on how the process of chemotherapy takes place and the importance of maintaining good oral hygiene. Even though John follows all the advice from the doctors, he still developed ulcers in his mouth due to chemotherapy. In response to these side effects, the nurses intervene to prevent the worsening of the side effects. Side effects of fluorouracil Fluorouracil is, a drug used in the treatment of cancer. It performs by making an irremediable reserve of thymidylate synthase. It interrupts the action of enzyme blocks hence hinders synthesis of pyrimidine thymidine which is a nucleoside for DNA replication (Winawer et al, 2003). Chemotherapy is generally used to kill any rapidly growing cells in the body thus killing the cancerous cells (De vita, 2001). Such rapidly multiplying cells are found in the mouth linings hence they fall victims to this chemicals. The reaction between the healthy cells in the mouth linings and the fluorouracil leads to formation of sores and ulcers. Since the occurrences of sores are hard to prevent, the extent of damage caused by the sores can be limited. In order to counter the side effects of chemotherapy, the patients need to be fully educated on the importance of good oral hygiene. They should be encouraged to regularly brush their teeth in order to prevent accumulation of germs in the mouth. ...
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