Chronic pancreatitis

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CHRONIC PANCREATITIS Case A 65 year old man with persistent lower abdominal pain and jaundice was detected with elevated levels of hepatobiliary enzymes. Abdominal ultrasonography revealed a diffuse hypoechoic swelling of the pancreas. Contrast enhanced ultrasound (CEUS) exhibited an enhancement of pancreatic parenchyma with inhomogenous staining.


General Description Chronic Pancreatitis (CP) is a heterogeneous, progressive disorder of the pancreas characterized by a spectrum of symptoms pain, inflammation, diabetes mellitus, and pancreatic damage leading to significant loss of both endocrine and exocrine functions of the pancreas (Witt and associates, 2007; DiMagno & Dimagno, 2006). Pathology involves fibrosis in the pancreatic parenchyma that manifests irregularly. Other organs in vicinity are also affected as consequence of the disease that may commence as an individual or a group of symptoms resulting from functional impairment of pancreas. The major clinical symptom of disease is recurring or persistent pain within the abdomens. The chief cause of CP in western world is alcohol abuse leading to alcoholic calcific pancreatitis (ACP). The other form of CP known as tropical calcific pancreatitis (TCP) prevalent in tropical countries is of uncertain etiology (Lee, 2011). Based on the risk factors CP is classified by the TIGAR-O (Toxic-metabolic, Idiopathic, Genetic, Autoimmune, Recurrent and severe acute, Obstructive) classification system (Nair tet al., 2007). ...
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