An author of the present writing intends to briefly introduce the main concepts of pharmacology in regard to nursing. The paper examines a particular case study of a patient who is being treated using drugs. The paper further discusses the altering the treatment process…
The dosage of drugs this patient receives will be initially higher than the standard recommended because the circulation loss means that the required amount of drug may not have the desired distribution effects (Dreyer, 2005).
Due to the gastrointestinal tract removal, the administrating doctor may decide that any treatment for PVD needs to be administered intravenously, and as such the dosage will be lower due to the differences in absorption via this method.
The nurse must monitor the progression of the symptoms of PVD. For example, if the patient was presenting with claudication, then the extent of this would need to be continuously monitored throughout the treatment period to see if this was improving. Additionally, blood pressure would need to be measured periodically to see if there was any improvement in blood flow throughout the vascular system (Birkett, 2002). The patient would also need to be monitored for cardiovascular events such as cardiac arrest or stroke as these occur more frequently in patients presenting with PVD (Dreyer, 2005).
Heparin is cleared from the body one of two ways, depending on the dosage used. At low doses, it is cleared through the reticuloendothelial system, and at high doses, both this and a renal clearing system are employed. As the dosages involved here are fairly high, and clearance is reduced in patients with cirrhosis of the liver or renal failure (Granger et al., 2001), we may make the assumption that there may be some issues in the renal clearing system in this patient and we may have to make further investigations into the state of the kidney. ...
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The purpose of this research is to investigate the following: drugs from natural sources; plants as a source of drugs ; microorganism drug sources; uses of natural products in drugs; drug design by computer modeling and strengths of computer modeling in drug design. The computer modeling in drug design holds a massive potential for the pharmaceutical industry
No inhalation of the spray should take place. An initial one-metered dose ought to be sprayed below the tongue at an attack’s onset, followed by another metered dose within a period of five minutes should pain relief not occur. It is recommended that it should not exceed two metered doses.
Absorption of the drug is dependent upon the dose total, duration of exposure, concentration of the dose and the site of exposure (Kwan, 2001). The drug absorbed well in the gastrointestinal system but undergoes extensive first pass hepatic transformation.
Smooth muscles are the muscles in the human body which are not under the conscious control of an individual that is they are involuntary. Smooth muscles are present in the most important operating systems of the human body. They are present in the blood vessels, in the stomach as well as the small and large intestine, the urinary bladder, the air passages, uterine cavity as well as the cavernosal sinuses of the penis and clitoris.
Medication administration process includes getting medical orders, writing medical orders on the (MAR) medical administration record, comparing the medical orders with the ones on the MAR to ensure they are correct, delivering and administering the medication to the patients, monitoring the patient’s progress and recording, storing and getting rid of expired, unused and contaminated medication.
It has successfully reduced GH and IGF-1 levels in 50-70% of patients and provides and IGF-1 levels. It also provides an IGF-1 normalization rate of approximately 30% in patients whom pituitary surgery has failed. Suppression of hormone is reached
She also noticed swelling around her ankles, but attributed it to the demands of being on her feet all day. After migrating to Britain her shortness of breath began to intensify. The condition worsened until she was
The first interest goes on how the drug interrupts the activity of the BCR-Abl receptor tyrosine kinase fusion protein. Studies show that it does so by acting against tyrosine kinase enzyme that necessitated the signaling cascade necessary the development of cancer. It is also significant to know why imatinib is effective with no many side effects.
Tyrosine kinases are the enzymes that catalyze the movement of ɣ phosphate group to the target protein from the ATP molecules. Tyrosine kinase molecules act as the membrane surface protein for the transduction of signals to the cytoplasm. Binding
For example, it inhibits the bioavailability of orally administered drugs by transporting them back into the intestinal lumen (Finch & Pillans, 2014). In humans, P-gp is found in abundance in the proximal renal tubules, the apical membrane of mucosal cells of the
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