Pathophysiology of Obsessive Compulsive Disorder

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Pathophysiology of Obsessive Compulsive Disorder (OCD)" Introduction The normal fear response to threatening stimuli comprises several components, including defensive behaviors, autonomic reflexes, arousal and alertness, corticosteroid secretion and negative emotions.


Obsessive compulsive disorder is an anxiety disorder, a compulsive ritualistic behavior driven by irrational anxiety such as fear of contamination, thereby repeated washing of hands and cleaning or articles is performed by the patient. The treatment of such disorders generally involves an amalgamation of psychological approaches as well as drug treatment (Katzang, 2009; Kaushik, 2011). OCD (Obsessive Compulsive Disorder) is characterized by repetitive anxiety- provoking thoughts (obsession) or repetitive behaviors aimed at reducing anxiety (compulsions). If such thoughts or actions are prevented or interrupted, the patient becomes anxious. It is chronic, prevalent as well as disabling condition that persists throughout life, hampers normal life of an individual and those who are associated with the OCD patient (Katzang, 2009; Kaushik, 2011). The disease is a chronic condition and no absolute reason could be formulated till date. Noteworthy contribution of studies involving OCD highlight the perception of the phenomenology and pathophysiology of obsessive-compulsive disorder (OCD) prevalent both in children as well as adults, affecting 1-3% of the population (Torres et al, 2006). Epidemiological understanding about OCD suggests that OCD has emerged as the fourth most common mental disorder across the world irrespective of cultural differences. ...
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