This research is being carried out at understanding the knowledge level and attitudes of pregnant women with the sickle cell trait from the Mississippi Delta about sickle cell disease. The philosophical basis of this study was anchored on interpretive phenomenology…
The paper tells that sickle cell anemia is an inherited blood disease where the body makes sickle-shaped red blood cells containing abnormal hemoglobin. Sickle cells are stiff and sticky and tend to block blood flow in the blood vessels of the limbs and organs. Blocked blood flow causes serious infections, pain, and organ damage. Patients are born with it. People who inherit a normal gene from one of the parent and sickle hemoglobin gene from the other parent exhibit a sickle cell trait. People with a sickle cell trait do not have Sickle cell anemia but have one gene that causes the disease. Approximately 2,500 people have sickle cell anaemia. This disease is now prevalent among pregnant women. A study on sickle cell anaemia in pregnant women is very significant for it will impart knowledge on this condition in relation to the woman’s and the in-born child’s health. However, the study is challenging as people have very little knowledge on this disease. The study seeks the relevance between the level of knowledge and the attitudes of pregnant women with the sickle cell trait from the Mississippi Delta and the sickle cell disease. To achieve this, the researcher will rely on an interview done in Mississippi Delta on Africa-American pregnant women and other relevant literature. Age, marital status, economic status, occupation, and level of education are some of the demographic variables the researcher used. According to the interview, only 20% of the respondents have enough knowledge about the sickle cell trait. ...
This implies that there is very little knowledge on the sickle cell trait hence the increased spread of sickle cell anaemia from pregnant women to their inborn children. Contents Contents 4 Background 6 Problem Statement 7 Purpose 8 Research Questions 8 Philosophical Basis 8 Definitions 10 Summary 11 Introduction 12 Concept Development 14 Major Related Studies 15 Summary 17 Study Design 19 Sample 19 Inclusion criteria 19 Interviews 20 Data Collection Plan 20 Ethical Considerations 21 Data Analysis Plan 22 Stage 1 22 Stage 2 22 Stage 3 22 Stage 4 23 Stage 5 23 Stage 6 23 Stage 7 23 Strategies for Rigor and Validity 24 Summary 25 REFERENCES 26 Introduction 32 Demographics of the Sample 32 Major Themes 33 Summary 35 Introduction 37 Limitations 39 Summary 41 REFERENCES 43 DEMOGRAPHIC TOOL 44 INTERVIEW QUESTIONS 46 CONSENT FOR PARTICIPATION IN RESEARCH STUDY 47 ASSENT TO PARTICIPATE IN RESEARCH STUDY 49 CHAPTER 1 INTRODUCTION Background Sickle cell disease is a disorder of the blood that is genetic in nature. Defective hemoglobin molecules that aggregate to form sickle-shaped, elongated, and inflexible rod-like structures that are unable to pass through small blood vessels (Papadakis et al, 2006) characterize it. As they are unable to pass through these small vessels, these sickle-shaped cells pile up together leading to blockages and starving tissues and organs of oxygenated blood. This results in regular periods of pain and is associated with damage to important body organs and tissues and can cause serious medical problems. Blockage may cause problems such as vaso-occlusive, hemolytic, splenic sequestration, and aplastic crises. Other medical conditions that may result include infections, stroke, priapism, ...
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Most pregnant women fear telling their husbands that they should go, be screened, and would rather give birth to children who have sickle cell anaemia. The contributory factor to sickle cell anaemia is the fact that most people lack education about the disease and so are not aware about it.
This paper take a look at some of the various ways that the disease affects the lives of people and how this disease can be controlled and managed without causing death. A series of articles and books have been used here as the main sources for getting the useful information used here.
SCD is a genetic disorder with autosomal recessive pattern of inheritance (Pelehach, 1995; Routhieaux, Sarcone, Stegenga, 2005) caused by a single-based mutation of adenine to thiamine resulting in a substitution of valine for glutamine at the 6th codon of the ?
One in 12 African – Americans and 1 in 100 Hispanic –Americans has sickle cell trait (CDC 2007). It also occurs in people who originate from the Middle East, India, and Eastern Mediterranean areas. The complications associated with this trait are mild and minimal and also people with this trait are as healthy as individuals who do not have this trait, but it assumes significance because children can inherit the sickle cell gene.
It is the oxygen carrier in blood. In other words, Hemoglobin is responsible for distributing oxygen to different body organs. It should be noted that adequate oxygen supply is necessary for many of the body organs to function well. So any defects occur to the Hemoglobin can cause problems in the functioning of different body organs.
The article describes the condition of Ryan Clark, safety of Pittsburgh Steelers and the reason why he has been restricted from playing in the upcoming game against the Denver Broncos. The writer has described the limitations a professional player has to face because of sickle cell trait and has also highlighted the underlying pathology of the blood disorder.
The diseased individuals inherit the genes from their affected parents and pass it on to their offspring. In sickle cell disease, abnormal haemoglobin S replaces the normal haemoglobin A due to alterations in the genes. The function of haemoglobin is to transport oxygen and deliver it to the different organs and cells of the human body.
Around 70,000 people, who are from sub African, even though there are some reports in India, some parts of central and South American areas, southern parts of Europe, and Caribbean regions mostly experience sickle cell anemia. Several children do not show any
Research shows that one in 12 African Americans and about one in 100 Hispanic Americans convey the sickle cell attribute, which implies they are bearers of the infection. Sickle cell sickness is brought about by a change in the hemoglobin-Beta gene found on chromosome 11.
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