Wegener's Granulomatosis.

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Abstract Wegener’s granulomatosis is an uncommon inflammatory process of the small arteries and veins, which involves classically the arteries and veins supplying blood to the lungs, nasal passages, and kidney tissues.


Wegener’s granulomatis has no known cause and although it affects people at any age, it usually affects the young or adults at their middle age. Fatigue, loss of weight, fever, shortness of breath, bloody sputum, joint pain, and inflammation in the sinuses are the common symptoms of Wegener’s granulomatosis. Several literatures are reviewed in this paper. Among patients with Wegener granulomatosis, narrowing of the lumen with some evidence of vasculitis resulted from thickened or fibrotic laryngeal wall. In some cases, granulation tissue replaces the mucosal lining of the larynx. Hence, laryngoscopy must be carefully performed to avoid bleeding from granulomas and dislodgement of ulcerations tissue among patients whom suspected diagnosis of Wegener granulomatosis is noted. Wegener’s granulomatosis is a fatal disease when it is not diagnosed and treated properly since it presents in various forms and deceives as manifestations of other diseases. Annotated Bibliography 1. Tanna, et al., (2011) Otolaryngologic Manifestations of Wegener Granulomatosis (WG) This article discusses that it is common to have otolaryngologic manifestation among patients with Wegener granulomatosis, and usually presents as nasal, sinus, ear, or tracheal manifestations in about 70 percent. ...
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