Metabolic syndrome (MetS) consists of pathological conditions that involve arterial hypertension, dyslipidemia, insulin resistance, and visceral adiposity, which lenience the progress of cardiovascular diseases.
Metabolic syndrome is increasing in first and third world nations,…
o the research carried out on US residents using the NCEP-ATP III standards, the unadjusted and age-adjusted prevalence of MetS were 21.8% and 23.7%, respectively (Byrne, 2011). Prevalence is higher when using IDF standards than using the NCEP-ATP III standards. For instance, in the comparison of the two organization’s standards, the age-adjusted prevalence of MetS established by NCEP-ATP III was 24.5%, whereas that of IDF was 43.4%. In other words, the prevalence of MetS rises consistently with increasing age unconventionally of sex, from 6.7% in individuals aged 20 to 29 years, to 43.5% for individuals aged 60 to 69 years, and 42% for individual aged 70 years and older (Byrne, 2011).
In addition, although there is no postulated information for adolescents and children, the overall prevalence of MetS in these groups is approximated to be 4.2% (6.1% for boys and 2.1 for girls), increasing to 6.8% amongst overweight and 28.7% in obese adolescents. Also, the study indicates that, the prevalence of MetS are similar for men and women, however, higher in black women than men, and lower in white women than men (Codario, 2011).
The underlying pathophysiology for MetS is still an issue of concern amongst various professional organizations resulting to inconsistencies in the way MetS is defined. Each definition has its benefit and drawbacks. However, insulin resistance and obesity has been identified to be the key contributing factors. Although insulin resistance is the core cause of glucose and fatty acid tolerance, it does not enlighten the alterations seen in endothelial dysfunction, lipid metabolism, systemic inflammation, blood pressure, and hypercoagulability. Laboratory measurement of insulin resistance is challenging, and, however, researches have indicated fasting insulin levels as a substitute, absence of analyze standardization makes this approach impractical (Awad, 2010).
On the other hand, other exponents have suggested that although abdominal obesity may ...
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Metabolic syndrome is increasing in first and third world nations, in both male and female and in adults and children. The prevalence of MetS depends on the measures applied to establish inclusion and the composition of the targeted population (ethnicity, age, race, sex).
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