Apathy and Depression Signs and Amnestic Mild Cognitive Impairment - Research Paper Example

Mild cognitive impairment (MCI) demonstrates noticeable symptoms to the affected individual and his family, especially when accompanied by significant memory loss. According to Zahodne & Tremont (2013), apathy and depression are distinct signs in amnestic MCI and for different patients, the two are associated with specific executive functions. For mental health nurses, the distinction of apathy and depression relative to the presented differential frontal lobes neuropathology patterns and the affected functions are crucial in planning and delivering appropriate care.

Article Summary
Zahodne & Tremont (2013), present the current diagnostic criteria as indicating that about 43% and 20% of patients meet apathy and major depression criteria correspondingly with and without baseline dementia. Through a multiple regression framework, apathy and depression are linked to specific cognitive abilities and functional status as presented in a sample of 90 elderly persons (with mean age 75.8 years) highly vulnerable to Dementia following amnestic MCI. For all participants, clinical assessments presented unbiased memory impairment and exclusion criteria of comorbid neurological illnesses, brain trauma history, and medical problems like cancer, and severe psychiatric disturbance (Zahodne & Tremont, 2013).

The independent variables were apathy, depression, education, and age, while the dependent variables were unprocessed scores on individual tests. The result linked depression to inferior exclusive functioning and was independent of age, apathy, and education. Conversely, apathy presented intricacies in Instrumental Activities of Daily Living or IADL and did not link to age, depression, or education. These findings proved that apathy and depression are distinctively associated with varying elements of executive functioning in amnestic MCI. For a mental health nurse, this information fundamentally contributes to the formulation of interventions aimed at fostering health, assessing dysfunction, and helping patients in regaining their coping abilities (Daniel, et al., 2014). Further, the nurse will understand the best coping strategies to include in self-care activities, and in the monitoring and administration of psychological treatment regimens.

Article critique
The research used a sufficiently large sample that leaves room for generalization. Additionally, the sample comprised of identifying elderly patients with amnestic MCI was comprehensively assessed by clinicians with a memory disorders centre (Zahodne & Tremont, 2013). Further, the assessment instruments’ selection focused on negligible common characteristics in the content, which coupled with multiple regressions, provided an improved ability to distinguish between apathy and depression influences.
However, the study does not utilize neurodegeneration biomarkers in the assertion that amnestic MCI presents underlying AD. Additionally, the study depended on patient reports from caregivers hence limited to indicators of psychopathology. The study sample, however, presents more females and is 99% Caucasians requiring additional research using other ethnic groups.

In the future, studies of apathy and depression in cognitively impaired patients should use biomarkers to distinguish focus on amnestic MCI could result in Dementia and not some other cognitive impairment resulting from other factors.
Conclusion
The article uniquely distinguishes apathy from depression in patients with amnestic MCI and this contributes significantly to the distinction of transition into normal aging and the progression towards dementia. Using apathy, mental health nurses can confidently identify progression towards dementia through identification of decreased performance of instrumental activities of daily living during preclinical dementia (Daniel, et al., 2014). The article also offers guidelines along which caregivers should focus on when assisting cognitively impaired patients with memory from a large sample clinically classified as having amnestic MCI.