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The Association of Chronic Cough and Gastroesophageal Reflux Disease in The Pediatric Population - Research Paper Example

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The Association of Chronic Cough and Gastroesophageal Reflux Disease in The Pediatric Population

Description of the issue to be explored: Cough is the most common symptom for which patients seek medical attention. In adults, cough variant asthma, postnasal drip or rhinosinusitis, and gastroesophageal reflux disease (GERD) are the most common causes of chronic cough in Western countries. A positive association between cough and weakly acidic reflux was found in a significant subgroup of patients with unexplained chronic cough (Blondeau et al., 2007, p. 723) thus, the evidence in adults leads us to suspect that GERD might be increasing as a cause of chronic cough in adult patients and the causal relationship can also be established in children (Irwin, 2006, p. 81S). The relationship between chronic cough and GERD is established in several studies that have revealed that GERD, singly or in combination with other conditions, is one of the most common causes of chronic cough in adults in the world. The prevalence in these studies ranged from 5 to 41% (Irwin, 2006, p. 81S). On the contrary, another study in adults showed a positive association between cough and GERD in significant subgroup with chronic cough but was not able to identify controlled studies that evaluated association of GERD and cough in children (Tolia, 2008, p. 258. But this relationship is yet to be established in the pediatric world because few studies in pediatrics have related GERD with chronic cough in children and is still yet to be explored and if found true can help in decreasing the rate of chronic cough rate in vulnerable population of children. Adult studies suggest that gastro-esophageal reflux disease (GERD) causes 21–41% of chronic cough. In adults with chronic cough, a small study has shown a non significant increase of airway neutrophils when compared to controls. In children with underlying respiratory problems studies shows chronic cough and airway neutrophilia has been reported to occur with GERD. However, there are no prospective studies that have examined the specific relationship between cough and objectively defined GERD in children without an underlying lung disease, and pediatric cough differs significantly from adult cough (Chang et al., 2006). Chronic cough in children, due to vulnerable immune system, often leads to more serious respiratory disease such as respiratory failure that impairs a person’s normal functioning as well as exhausting family funds in diagnostics and medications for complications when caught unaware of the condition. For this matter the importance of defining the common causes of chronic cough in children might be the best solution to target the impending problem and since GERD is associated with unexplained chronic cough in adults the possibility of being in children can be a probable cause of increasing chronic cough rate in children. Cough in adult and children have differences that’s why the relationship of chronic cough and GERD in children needs to be established though clinical researches tells the relationship in adult patients (Chang & Glomb, 2006). Scope of topic The scope of the topic area will tackle on the association of chronic cough and GERD in children. Though some data may refer to results of some researches regarding chronic cough and GERD in adult patients, it is mainly for the purpose of comparison alone. The topic will not cover other conditions associated with GERD or chronic cough alone in pediatric patients to avoid misconception and for unity in the ...Show more

Summary

Michelle McGuire FNP III Evidence Based Practice Paper Topic: The Association of Chronic Cough and Gastroesophageal Reflux Disease in Pediatric Population. Is there a causal link between chronic cough and GERD in pediatric patients? I. Primary research question:  1…
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