It is however important to realize that the administration of Ipratropium should be managed in a way that makes its use safe for the patient.
The delivery of Ipratropium is carried out in the form of aerosolized solution through the use of a metered dose inhaler. The recommended dosage of Ipratropium in inhaled solutions is 500 mcg given 6 or 8 hourly. Therapeutic benefit starts within 30 seconds and reach its 50% level by the end of 3 minutes; this effect persists for about 6 hours. Being a quaternary ammonium compound, ipratropium carries a positive charge and is therefore not easily absorbed from lungs; hence systemic absorption is minimal which makes it a safe compound. Significant improvement in pulmonary function becomes apparent within a time span of 15 to 30 minutes. Combinations of ipratropium and albuterol are also marketed, the use of which should be avoided in patients who have a known allergy to Peanuts, since soya lecithin is used as a career in such combinations (Lehne, ...
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The purpose of this research is to investigate the following: patho-physiology and pathology (mechanisms responsible for causing asthma; symptoms of asthma; types of asthma) and pre-hospital/medical management (diagnosis of asthma; family/medical history of the victim; taking a physical exam; the lung function test; the challenge test; treatment of asthma).
Asthma is a chronic inflammation of airways characterized by continuous and developing inflammatory process that later produces variable clinical presentation such as cough, wheezing etc. Acute inflammation results in broncho-spasm while chronic inflammation affects airway caliber and airflow, thus causing bronchial hyper-responsiveness.
According to one research paper (Allan & Devereux, 2011), this is one of the most common chronic diseases in the world, with 300 million people suffer from it currently, and projections show that a 100 million more people join to this number of asthma patients by 2025 (Allan & Devereux, 2011).
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