Parkinson’s disease received attention by authors in 1817when doctor James Parkinson described in an essay referring to the diseases a shaking palsy. For over a century, the name shaking palsy remained in use in reference to the diseases. Many people did not have the basic…
Usually, the nerve cells that degenerate because of Parkinson’s diseases are those located in the basal ganglia. In addition, Parkinson’s disease contributes to the loss of nerve cells in the substantia nigra, which is a component of the brainstem (Carranza 2013, p. 67). Worth noting is the fact that the cells affected by Parkinson’s are responsible for the production of dopamine, which is a critical neurochemical messenger playing a key role in coordinating normal movement. Usually, dopamine forms the start of a circuit of messages responsible for the functionality of normal movement. Unfortunately, Parkinson’s disease affects nerve cells that produce dopamine reducing the level of stimulation in the receptors involved in the coordination of normal movement. More specifically, the receptors in the basal ganglia circuit fail to undergo active stimulation resulting in challenges in movement. Patients with this disease, suffer from movement with tremors, loss of balance, stiffness, as well as slow moving. This paper will describe the signs and symptoms of Parkinson’s disease, as well as the current treatments used in treating the disease.
As highlighted above, Parkinson’s disease causes the degenerations of neurons. However, researchers have been unable to describe the specific reason or cause that triggers the degeneration of neurons. The degeneration of neurons remains to be an area of interest or many researchers who understand the social effects, as well as the economic implications of the disease. In addition, the progression of the diseases can be highly debilitating denying an individual the freedom to move around or have a proper body balance (Chaudhuri 2009, p. 78). Evidently, the past few years have seen many researchers make remarkable progress in understanding the disease. Acceleration of such understanding has helped manage the condition of many patients with the disease. Current ...
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“Parkinson Disease Research Paper Example | Topics and Well Written Essays - 1750 Words”, n.d. https://studentshare.net/nursing/736916-parkinson-disease.
Knowledge in some studies regarding treatment of basal ganglia disorders as well as the challenges in its treatment highlight the understanding of the disease. Basal ganglia disorder could be treated in several ways. However, this all depends on the type of particular basal ganglia disorder.
It is assumed that most patients with idiopathic Parkinson’s disease may not develop all the symptoms related with the condition. The actual reason for the fluctuations of symptoms from time to time has not yet been proved. However, it may be attributed to antiparkinson medications.
(NIH, 2004) Parkinson’s leads to tremors and shaking of head, trauma, and difficulty with walking, movement and coordination. Research suggests that Parkinson’s impacts around 500,000 people in the United States alone and the total cost of the disease to the nation is estimated to be around $6 Billion annually (NIH, 2004).
It should be noted that fertilization stimulates the process of cell formation and embryonic cells formed immediately after fertilization has huge value and utility than any other cells formed after few months or years. Embryonic stem cells has the ability to replicate indefinitely and it can give rise to any fetal or adult cell type.
The etiology of the disease has been discussed in relation to both the genetic and environmental factors. Important genes causing inherited Parkinson’s disease are LRRK2, PINK1, Parkin gene, SNCA and DJ-1. The mutations can result either in dominant or recessive Parkinson’s disease.
Adopting a well stipulated indicator for measuring the performance before and after receiving physical therapy by the studied patients had been a significant criterion for selecting studies for this literature analysis. Other criteria for selecting theses particular studies include technical and convenience related considerations.
Based on preliminary findings that lack of 1, 25-dihydroxyvitamin, a form of vitamin D, leads to poor bone density among the patients, the researchers implemented an experimental design in which 43 participants received 1a-hydroxyvitamin D3 treatment while 43 other participants did not receive the treatment.
The actual reason for the fluctuations of symptoms from time to time has not yet been proved. However, it may be attributed to antiparkinson medications. Bradykinesia or slowly voluntary movement is one of the major
The etiology of the disease has been discussed in relation to both the genetic and environmental factors. Important genes causing inherited Parkinson’s disease are LRRK2, PINK1, Parkin gene, SNCA and DJ-1. The
Treatment during the early stages of the disease has progressed, and proof indicates that dopamine agonist monotherapy may put a stop to the change in response to the progression of the disease. Treatment during the further stages of the disease concentrates
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