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Vascular Access in Continous Renal Replacement therapy
Pages 5 (1255 words)
Name: University: Course: Tutor: Date: Vascular Access in Continuous Renal Replacement Therapy Acute renal failure (ARF) also referred to as acute kidney injury alludes to sudden slowing of the kidney’s function resulting in elevation of plasma creatinine, blood urea nitrogen and reduced urine output (Rabindranath, Adams, MacLeod and Muirhead, 2007, p.
24). CRRT uses diffusion (haemodialysis), convection (haemofiltration) or combines these two methods (heamodiafiltration) in order to achieve solute removal from the blood. Small molecular weight substances like potassium, urea and creatinine are efficiently removed through haemodialysis (Kellum, Mehta, Angus, Palevsky and Ronco, 2002, p.1858). For larger solute molecules, heamofiltration is the most efficient method of their removal in comparison with dialysis. In haemofiltration, filtration of plasma through the semi-permeable membrane is caused by hydrostatic pressure. In addition, solutes cross the membrane alongside the plasma which results in convective solute transport flowing in the same direction as water (Medve, Preda and Gondos, 2010, p. 104). Therefore, haemofiltration needs the use of replacement fluid to avert excessive removal of fluid, electrolyte depletion as well as iatrogenic acidosis. Since the plasma solute concentration is the same as that of the removed filtrate, concentration of the solutes in the blood plasma remaining need to be diluted using substitution fluid. ...
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