Evidence Based Article

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Risk assessment model for Chemotherapy-induced Neutropenia in Breast cancer Name: Institution: Date: Risk assessment model for Chemotherapy-induced Neutropenia in Breast cancer Summary Implementing an Evidence-Based Risk Assessment Tool to Predict Chemotherapy-Induced Neutropenia in Women with Breast Cancer by Li-Lu Chang, Susan M.


The authors point that the use of the Chemotherapy-induced neutropenia has caused delays and reductions in patients with early stages of breast cancer and has compromised the treatment outcomes especially with treatable tumors. The authors also state that febrile neutropenia (FN) has shown a high risk for serious complications in cancer patients and requires quick medical intervention for cancer patients. The rates of FN can, therefore, be reduced by the prophylactic granulocyte colony-stimulating factor that its efficacy has been proven by several randomized controlled trials and meta-analysis of the trials (Chang, Schneider, Chiang, & Horng, 2013). The authors advice that clinicians must first assess patients carefully and accurately before introducing chemotherapy and applying primary prophylaxis to patients who are at a greater risk because it is beneficial clinically and is cost effective. The authors also explain that the individual risk assessment for neutropenia events in deciding the use of prophylactic G-CSF, as recommended by different associations on the treatment of cancer, does not give clinicians with a clear way for assessing risks. ...
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