Abstract of a Microbiology Paper Beig FK, Ahmad F, Ekram M, Shukla I. Typhidot M and Diazo test vis-a-vis blood culture and Widal test in the early diagnosis of typhoid fever in children in a resource poor setting. Braz J Infect Dis. [Internet] 2010 Dec [cited 2011 March 24];14(6):589-93: Available from http://www.ncbi.nlm.nih.gov/pubmed/21340299 Typhoid fever has emerged as one of the major public health challenges all over the world…
The gold standard for diagnosing typhoid fever is isolation of organism through blood culture. But lack of expertise and equipment for this test makes it unusable in a peripheral setting. Widal test is also useful, but is of no value in endemic areas. Currently, this test is regarded as non-specific and inaccurate. Because of these limitations of the popular tests, several assays and serological tests have been developed but have not been found to be optimal. Thus, the need of the hour with regard to typhoid testing is a test that is not only simple, but also reliable and carried out in small laboratories in the peripheries. Two such tests which merit importance are typhidot M and Diazo tests. In this study, Beige et al prospectively evaluated typhidot M and Diazo tests vis-a-vis blood culture and Widal test in children. In this prospective study, children aged 6 months to 12 years with fever of more than four days duration and with clinical suspicion of fever were enrolled. Those with other suspected diagnosis were used as controls. ...
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