Essay sample - HIV and HBV

Pages 2 (502 words)
Download 0
Exact determination of HIV and HBV behavior upon contact to previously healthy cells is crucial to the formulation of effective medical response. One approach practiced by scientists and researchers is to model in vitro (test tube conditions) in the hope of determining changes in gene expression for the formulation of candidate vaccine pathogens…


This in vitro study is called transient transfection cell culture systems and has been used to establish sensitivity or cross resistance to analogues. Imperative in this activity is the acquisition of quantitative real time data and previous knowledge on the replication and pathogenesis of HIV or HBV. Any difference in expression of the transfected cell is identified and analyzed.
Another approach is to introduce derivatives from certain sources that can serve as potent inhibitor of in vitro HIV or HBV replication. For example, synthetic DNA molecules called antisense oligodeoxynucleotides (ODN) were administered to cells transiently and stably transfected with HBV protein encoding plasmids. The cells were observed for any HBV replication and pathogenesis for 48 hours. It was found that there ODN effectively inhibited viral protein expression and replication. ( Karayiannis, 2003)
Animal models have also been very useful in understanding the replication and pathogenesis of the virus mentioned. Many of the models are na've primates such as chimpanzees, rhesus macaques and Aotus monkeys. HBV or HIV carrier animals are administered with potential cures. ...
Download paper
Not exactly what you need?

Related papers

Science on television and in film
Mass media, especially television, printed media and the Internet benefits from the misunderstanding, superstitions and fears of general public who live in the world that is completely dependent on science and on scientific achievements.…
6 pages (1506 words)
Amino Acide
Polymerization is a common reaction, due to excessive use of amino acids to ensure coupling during each synthesis phase. As a result, a series of deprotection phases are added to the synthesis process which takes the following form:…
7 pages (1757 words)
These plates radiate from the central vein. Each of these plates is of thickness of two cells. Between the adjacent cells lie small bile canaliculi that empty into bile ducts in the fibrous septa separating the adjacent liver lobules.…
8 pages (2008 words)
In this sense it is meant that the review should be constructed in such a manner that the researcher/researchers can either use it as a stand-alone published material that can assist other researchers with similar topical considerations in their own research or the researcher/researchers can use the review exclusively as an assisting part of their own research on the topic. This brings out the…
8 pages (2008 words)
randomised clinical trials
The critical resource of D G Altman's "Practical Statistics for Medical Research" was also available at Google Books. Various search terminologies were used which include "Evolution/History/Review of Clinical Trials", "Ethical issues of clinical trials", "Nazi medical war crimes", "Nuremberg/Helsinki/Belmont" codes. Formulae for the sample size calculations were also accessed from journal…
19 pages (4769 words)
Western Blot and its Applications.
Western blot analysis can detect your protein of interest from a mixture of a great number of proteins. It can give you information about the size of your protein (with comparison to a size marker or ladder in kDa), and also give you information on protein expression (with comparison to a control such as untreated sample or another cell type or tissue). It can analyze any protein sample whether…
4 pages (1004 words)