Breast cancer, as well as ovarian cancer, is a large problem of medicine and both are life treating, especially for women. These cancers are of particular importance because they are promoted by estrogen. In 2000, approximately 130,000 women died of breast cancer; nearly two thirds of these women were postmenopausal. In pre-menopausal women estrogen is produced in the ovaries, so reducing estrogen from other sources it not important, but in post menopausal women most of the estrogen in the body is produced in the adrenal gland from conversion of androgens and also from adipose tissue through special enzyme called aromatase. The large influence of the estrogen produced outside the ovaries by aromatization is clear. In postmenopausal women, their estrogen comes from the actions of atomatase-final step in the pathway of estrogen biosynthesis by creating an aromating ring in the steroid molecule, and so its inhibitor may be used to treat estrogen tumors, and so, effective treatment in breast cancer is aromatase inhibitor. Also, it is used in women when their ovaries are no longer producing estrogen. ...Show more
Aromatase inhibitor represent a class of antiestrogens, a drug that inhibits the enzyme aromatase by lowering the level of estrogen estradiol ,by process called aromatization. There are two types: first one is irreversible steroidal inhibitor and the second one is non-steroidal inhibitor such as anatrazole which inhibits the enzymes by reversible competition…
Under poetry exists different genres such as the Narratives and Epics (Iliad, Nibelungenleid and Mahabharata), Dramatic (Hamlet and Faust) and the Lyrical ( the 14 line Sonnets). The topics of poems range from mundane subjects to tales of love, war or a combination of both and many more topics.
Fred Fiedler developed the first contingency model for leadership, known as The Fiedler contingency model. It is suggested the model is "the most comprehensive programme of research ever conducted on leadership" (Fiedler, 1967, as cited in Elkin and Inkson, 2000, p.
Based on the changes in dietary patterns of individuals, in a normal healthy body glucose production by the liver is regulated and so is the case with the uptake of glucose by the muscles and other tissues. The two crucial mediators in this regulatory process are insulin and glucagon.
These four categories together form the whole Marketing Mix which in turn, if implemented effectively, can make the business successful. It is compulsory for every organization to use four of these approaches effectively to get successful in their businesses.
By contrast, the abolitionists see the impact of executions as a statement of pervasive importance about the relationship between the government and the individual. Abolitionists in the United States view capital punishment as a fundamental political issue; proponents usually assert that the question is neither fundamental nor political.
In the class of actions under tort law which is negligence,1 public policy impinged on the judicial decisions by graduating the the duty of care imposed upon the defendant of the case. Because tort is an intermediate source of liability standing between contract and crime - imposing liabilities based on wrong rather than on consent, it is a continuing judicial concern, as may be gleaned as emerging from a series of cases, for the identification of the unifying principle within which liability could fit in.
The third is that cnceptual cmpartmentalizatin in science ften leads t a dissciatin with the previus wrk in the field. These things are cnsidered f scientific relevance t the develpment f high quality nursing service. The impetus fr this paper was the idea that the cncept f evidence-based nursing represents smething f a paradx.
And, in the age of the information revolution, the quality of strategic decision-making is greatly influenced by the quality of information available for analysis and appropriate decision-making. The need for quality information, needless to say, suggests the significance of marketing research in strategic marketing decision-making and in ensuring business success, particularly so in the present business environments characterised by the pressures of global competition and fast paced changes in information and communication technologies as well as constantly evolving marketplaces and consumer choices.
Levels of thyroxine, triiodothyronine and thyroid stimulating hormones are checked basically for hyper and hypo thryroidism. The basal metabolic rate is also determined because it increases greatly in hyperthyroidism whereas in hypothyroidism it is reduced.
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