Major Histocompatibility Complex - Essay Example

Only on StudentShare

Extract of sample
Major Histocompatibility Complex

The role of immune responses and polymorphism brings about changes to parasitic responses and individuals master immune responses against pathogenic responses. In this discussion features of the major histocompatibility complex are highlighted and the mechanisms and functions of the immune system are also discussed in terms of pathogenic reactions and the role of the MHC. The importance of genetic diversity, selective pressure and polymorphism would also be discussed to suggest evolutionary changes, genetic diversity in the population and the influence of MHC on social behavior.
A description of the MHC or Major Histocompatibility Complex could suggest that MHC is a gene cluster. The MH complex consists of four million base pairs of DNA and contains 128 genes as well as 96 pseudogenes (non-functional gene remnants). The MHC is thus a multigene family, has a large cluster of genes encoding key receptor molecules that aids in the binding of foreign peptides to immune cells and this in turn leads to a successful immune response (Klein, 1986).
The vertebrate immune system has the MHC as its core and it is a multigene family encoding receptor molecules that binds and recognizes foreign peptides for immune responses and immune cells. ...
Download paper


MHC or major histocompatibility complex is characterized by immune responses. Genetic diversity is noted as the main feature of MHC and MHC is considered as the most polymorphic genetic system. MHC exercises a pathogen driven selection which is mediated through frequency dependent selection or heterozygote advantage…
Author : mbotsford

Related Essays

Human Visual Perception
Moreover, the fibers of each optic tract synapse in the dorsal lateral geniculate nucleus and from here, the geniculocalcarine fibers pass by way of the optic radiation to the primary visual cortex in the calcarine area of the occipital lobe (Guyton & Hall, 1996).
4 pages (1004 words) Essay
Globalisation: Reshaping the Geographical Imagination
(McMaster 2005, n/p)
4 pages (1004 words) Essay
Hypersensitivity results into a systemic inflammatory response leading to a spectrum of problems ranging from just runny nose to anaphylactic shock to death. This life-threatening aberration of normal immune process, that is, anaphylactic response of a sensitized human appears within minutes after administration or exposure to the specific antigen and is manifested by respiratory distress, often followed by vascular collapse or shock without antecedent respiratory difficulty. Cutaneous manifestations exemplified by pruritus or urticaria with or without angioedema are characteristic. Along with...
10 pages (2510 words) Research Paper
C-reactive protein as a novel biomarker
This process leads to the formation of foamy macrophages and atheromatous plaques and, finally, to atherothrombotic disease. Atherosclerosis is associated with high morbidity and mortality.
8 pages (2008 words) Essay
Calcium within the Human Body
A fascinating interplay of pathways and signals are involved in calcium regulation. As research and new technologies evolve, new aspects are elucidated in these complex mechanisms. Various animal models have been used in order to understand the cellular responses and the hormonal regulation (Eckermann 2008).
6 pages (1506 words) Essay
Cellular Microbiology
(Institute of Materials, Great Britain, P. 223) The importance is far reaching, from environmental O2 /CO2 balance to the synthesis of artificial herbicides that act on unwanted herbs by blocking some important steps in this energy producing process. The chlorophyll pigment alone has lead to new avenues for thoughts and research on the importance of photosynthetic processes and has paved the way for the synthesis of certain medicinal drugs exploiting its photoprotective mechanisms for preventing light induced damage of cells. The chlorophyll research has added to the significance of this novel...
8 pages (2008 words) Essay
Got a tricky question? Receive an answer from students like you! Try us!