The bacterial properties (virulence factors) of these organisms favorable for colonization
Can acquiring MS at early age influence incidences of dental caries in later years
MS transmission routes.
Whether nonmutans in oral flora affect colonization and or action of Mutans.
Research question: what are the host and microbe factors influencing oral colonization by MS in young children.
Materials and Methods: In the course of research paper preparation the microbiological as well as molecular biological approaches taken by the researchers would be presented. These are used to differentiate between mutans and nonmutans from oral cavity, production of mutacin and glucan, identification of different MS genotypes etc. The methods of longitudinal surveys used in various studies are also part of the intended research.
Results and discussion: The results obtained in the chosen host and bacterial factors responsible for MS colonization would be presented. For the convenience of explanation of results the results and discussion are combined in this paper. The manuscript would contain at least a total of 7-8 tables and figures. These are integrated in the text and attached as per the instructions.
The title page with author's (of this paper) name and affiliation, abstract, acknowledgement and a bibliography of all sources of literature also to be included in the paper.
Oral colonization of mutans streptococci (MS) in young children
The aim of this study was to evaluate influence of host and bacterial factors on oral colonization by MS in young children. It was observed during the course of investigation that children acquired MS by horizontal as well as vertical transmission. More...
As the report stresses various surveys, in many countries, have indicated presence of a type of dental caries, early childhood caries. These decays of primary teeth lead to dental abscesses and toothache which often requires anesthesia for treatment. Colonization by mutans streptococci (MS), particularly S. mutans and S. sobrinus, is the major cause of ECC in young children. There are disputes regarding time of entry of oral MS in young children and whether these are part of normal oral microflora or not. Since colonization by MS could be targeted to relieve young children from experiences of ECC, the paper would critically discuss host and microbial factors important for transmission and colonization of these bacteria. From this paper it is clear that mutans was also detected in predentate children, despite a low caries rate. Together, these reports suggest that children may be colonized by S. mutans before the "window of infectivity" opens. A predentate infant is not likely to have MS in salivary flow since swallowing occurs fast while bacterial divisions are only 2-4 times. MS could instead persist by forming adherent colonies on mucosal surfaces. Tanner and coworkers have demonstrated that the furrows of the tongue appear to be an important ecological niche for oral MS. It is contrary to the prior observations that MS colonization occurs only at the time of primary teeth eruption.