This research paper examines Leonardo da Vinci's life. He was born on April 15th, 1452 to Piero da Vinci, a notary, and Caterina, a peasant woman, at the hill town of Vinci, Italy. Even though not much is known about his early life, this has been the topic of historical conjecture In his numerous notebooks, Leonardo struggled with differentiating between the perception and painting of a scene which he summarized as the difference between monocular and binocular vision. Leonardo da Vinci could not create on canvas, in Ames’ terminology, an equivalent of configuration. He may have had little knowledge of ocular anatomy but his use of optics to the eye is spectacular. In addition, Leonardo possessed observational skills that had no match and his ability to generate virtual reality on canvas was without equal. Leonardo da Vinci (1721) noted that even though a painting may be carried out with the best art and finished perfectly, with consideration of its lights, contours, colors, shadows, it can never show the relief possessed by a natural object unless these qualities are looked at from a distance with a single eye. In other words, the perception of deepness in a painting is not as complete as that of a natural scene seen with both eyes. He struggled for long with the contrast between binocular and monocular vision. In one of his notebooks, Leonardo wrote down how he had to repeat his experiments several times before coming to a conclusion. The reason he gave for this was that the subjects of study were numerous.