Multidrug Resistance in Mycobacterium Tuberculosis - Essay Example

Only on StudentShare

Extract of sample
Multidrug Resistance in Mycobacterium Tuberculosis

Thus, the world is threatened with the risk of multi-drug resistant tuberculosis in the form of a pandemic that thrusts on the financial state of the State. Apart from that, emergence of immune deficiency viral disease has also predisposed to rapid spread of multi-drug resistant tuberculosis. Present knowledge on the molecular basis of development of multi-drug resistance may be utilized to develop a diagnostic protocol applying improved genetic analysis to detect the point mutations in the multi-drug resistant strains of Mycobacterium tuberculosis, so the clinicians may diagnose and treat this disease better. This research proposal aims to analyze the scientific basis of such a protocol, not only to add to the existing knowledge but also to devise a method that at least theoretically has far-reaching implications in the control of the disease that could be a global threat.

Background: Recent years have witnessed a phenomenal upsurge in number of reported cases of multi-drug resistant Mycobacterium tuberculosis (MDR-TB) infection. Multi-drug resistant tuberculosis is defined as bacterial isolate strains that are resistant to both isoniazid and rifampin with or without resistance to other anti-tuberculosis drugs. Since there is a gradual increase in the number of cases throughout the world including the developed countries, World Health Organization (WHO) has termed this as a global emergency. The rise of MDR-TB showing resistance to conventional treatments is a serious threat to control of tuberculosis disease load throughout the world in high-prevalence countries and low prevalence countries as well. ...Show more


Despite advances in different fields of Medicine and drastic improvements in diagnostic technological know-how, the diagnosis and management of tuberculosis remain elusive. …
Author : ferne44
Save Your Time for More Important Things
Let us write or edit the essay on your topic
"Multidrug Resistance in Mycobacterium Tuberculosis"
with a personal 20% discount.
Grab the best paper

Related Essays

Tuberculosis TB
Nearly 2 million people die of the disease worldwide every year (Frieden et al., 2003). The disease becomes dangerous because its symptoms are not always visible and the bacteria may lie dormant for more than twenty years before attacking the body parts and damaging it.
4 pages (1000 words) Essay
The bacterium Mycobacterium tuberculosis is the causative agent of TB in humans. Figure 1: Mycobacterium tuberculosis (also called tubercle bacilli) The World Health Organization (WHO) reports that the bacterium infects a third of the world’s population resulting in about 8 million cases and a mortality of 1.45 million annually (WHO, 2011).
8 pages (2000 words) Essay
Short Answer Questions
Chronic medical conditions are those ailments that persist for at least six months and the most common include cancer, asthma, HIV, diabetes mellitus, stroke, cardiovascular disease and musculoskeletal conditions. Chronic disease management enables general practitioners to plan and also coordinate healthcare for patients with chronic conditions (AU., 2013).The plan will also incorporate other healthcare provides or specialists in case a multidisciplinary team based approach is necessary.
6 pages (1500 words) Essay
This gives rise to antibiotic resistance over time and the patients are at risk of developing resistant infections in future. These can cause serious illness or even death in the most resistant cases (U.S. Department of Health and Human Services, 2013). Antibiotic resistance is a growing pandemic which has resulted in serious infections and death due to resistance bacteria.
5 pages (1250 words) Research Paper
Epidemiological report- tuberculosis in Leeds uk and it associated risk factors immigration ethnicity and deprivation
Findings support the hypothesis that tuberculosis infection was introduced into Leeds west, Yorkshire by airborne transmission from the sputum of an infected individual. These findings also examine the effect of ethnicity and deprivation in regard to the prevalence rate of tuberculosis in the city of Leeds.
10 pages (2500 words) Essay
Betalactam Antibiotics
They are mainly to be thought of as agents which would find great potential as second line components of a multidrug treatment regimen, given in tandem with first line antitubercular drugs. They are expected to work best when administered in the early phase of treatment, and should typically be used in conjunction with beta-lactamase inhibitors.
20 pages (5000 words) Essay
is one of the assays suitable on its own? If not how might they be used in combination?) Numerous factors are considered when
2 pages (500 words) Case Study
There are two major complications that occur within the respiratory system; influenza and pneumonia. Both diseases affect people within different age groups. In addition, young children (less than two years) and adults (65
1 pages (250 words) Assignment
Active tuberculosis case finding and detection of drug resistance among HIV-infected patients: A cross-sectional study in a TB endemic area, Gondar, Northwest Ethiopia
Tuberculosis (TB) is one of the leading opportunistic infections that lead to significant morbidity and mortality. Diagnosis of TB is usually difficult because of non-specific symptoms, negative results of sputum
12 pages (3000 words) Essay
Find out how much would it cost
to get a custom paper written by a pro under your requirements!
Win a special DISCOUNT!
Put in your e-mail and click the button with your lucky finger
Your email