This paper tells that54-year-old Josef is suffering from diabetes mellitus- type-2. Decreased ability of the peripheral tissues to respond to insulin and inadequate secretion of insulin by beta cells of the pancreas are the main metabolic defects in type-2 diabetes…
This is because there is an inverse correlation between fasting plasma free fatty acids (FFA) and insulin sensitivity. Central obesity is more associated with diabetes. Intracellular triglycerides are markedly increased in muscle and liver tissues in obese individuals because the increased circulating FFA are deposited in these organs (Kumar, 1195).
It is very important for a patient suffering from diabetes to take appropriate diet and exercise to maintain normal glucose levels. In the long-term, diabetes leads to 3 main conditions, the disease of the eyes (retinopathy), nerves (neuropathy), and kidneys (nephropathy) (Kumar, 1195). These effects are due to the damaging effect of hyperglycemia on the blood vessels in these tissues. Tissues like nerves, lenses, kidneys and blood vessels do not require insulin for transport of glucose. Hence blood glucose can enter the cells without insulin. The hyperglycemia leads to increased intracellular glucose which is then metabolized by aldose reductase to sorbitol and then fructose. This process uses NADPH which gradually gets depleted resulting in oxidative stress in the cells. Thus damage to the organs occurs (Kumar, p.1195). In the retina, increased intracellular glucose stimulates the de novo synthesis of diacylglycerol from glycolytic intermediates which further causes activation of protein kinase C. Protein C causes revascularization in the retina and diabetic retinopathy, increased deposition of the extra cellular matrix, fibrinolysis and production of pro-inflammatory cytokines (Kumar, p.1195). Thus various tissues in the body are damaged as a result of blood hyperglycemia.
Studies have shown that hyperglycemia appears to be the determinant of microvascular and metabolic complications and that glycemia is much less related to the macrovascular disease. ...
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(What Habits Lead to Diabetes Mellitus Essay Example | Topics and Well Written Essays - 1500 Words)
“What Habits Lead to Diabetes Mellitus Essay Example | Topics and Well Written Essays - 1500 Words”, n.d. https://studentshare.net/health-sciences-medicine/345506-case-study-diabetes-mellitus-2008.
DIABETES MELLITUS. Approximately thirty one million people in the whole world die from the four major chronic, non-communicable diseases. The diseases are such as diabetes, cancer, respiratory disease and heart disease. Chronic disease term refers to the above four named non-communicable diseases according to Oxford Health Alliance (www.
Insulin is an important hormone that plays a key role in metabolism and storage of glucose in a human body. Therefore, the main causes of increased blood glucose level include a decline in insulin levels, decrease sensitivity towards insulin, increase production or decreased metabolism of glucose.
One of the deadly complications of diabetes is coronary artery disease which is attributed to imbalance in lifestyle. Diabetes has affected approximately 200 million individuals worldwide and expected to double by 2030 (Bottino & Trucco, 2005).
Also known as type I diabetes, juvenile diabetes and diabetes mellitus. (Condition: Insulin dependent Diabetes mellitus, 2008)
IDDM is caused by a reaction caused in the body such that the immune system looses the capability of insulin-secreting cells in the pancreas.
s mellitus is a group of chronic metabolic disorders culminating in the elevation of blood glucose levels due to defective insulin secretion, action or both. Diabetes causes both, microvascular diseases (blindness, kidney failure and nerve damage) caused by damage to small blood
He author explains that Diabetes mellitus is classified according to the pathophysiologic mechanism leading to hyperglycemia. Type 1 diabetes, also known as insulin-dependent or childhood-onset diabetes, is characterized by an absence of insulin production. Type 1 diabetes can occur at any age.
Type II diabetes mallitus is a familial disease in some cases where it runs in families. In such cases, it is most commonly a result of weight gain. Obesity is a major risk factor for type II diabetes mallitus in those
In this intervention, the patients have to avoid consuming dietary that contains saturated fats. In addition, the diet must also contain lower levels of carbohydrates, which enable the reduction of blood glucose levels. Glycaemic Control: In this intervention, the patient uses insulin to enhance the body’s ability to regulate sugar levels.
The RN can help this patient cope with the diagnosis by first educating the patient about type 1 diabetes and its impact on the patient’s body. By so doing, the patient will understand that the illness is a
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