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Estrogen and progesterone ( Advanced pharmacology) - Essay Example

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Administration of estrogen and progesterone by means of oral, transdermal or depot injection methods inhibits ovulation by the process of negative feedback inhibition. These hormones exert their action by inhibiting the secretion of gonadotrophins like lueteinizing hormone (LH)…
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Estrogen and progesterone ( Advanced pharmacology)
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Estrogen and progesterone ( Advanced pharmacology)

Pills containing progesterone also act by secreting thick cervical mucus which blocks the movement of the sperm beyond the cervix. There are many different types of progesterones like synthetic or oral progesterone, crinone, injectible progesterone and progesterone suppositories. Before recommending an oral contraceptive pill which is usually a combined oral contraceptive pill (COCP) to the client, a detailed clinical history must be taken. The history should cover information like the previous and current medications taken by the client, herbal and over the counter remedies and drug usage. In case of women above 35 years and women with a history of cardiovascular disease, diabetes, migraines, gall bladder disease and pulmonary hypertension, COCP recommendation should be avoided (Petitti, 2003).
The oral contraceptive may either be a combination birth control pill or a minipill. The combination birth control pill contains both progestin and estrogen and different combinations of active and inactive pills which may be conventional or continuous dosing type. Progestin is the only constituent of the minipill. The combination birth control pills may be monophasic or triphasic. In case of a monophasic birth control pill, every active pill comprises of the same quantity of progestin and estrogen, whereas the triphasic combination birth control pill contains three different types of pills that contain different hormones taken for a period of 3 weeks. Other than oral contraceptives, there are also novel approaches available to prevent conception. Ortho evra is a trans-dermal patch that is worn on any region of the body like abdomen, buttocks, upper arm or upper torso except the breasts that delivers progestin and estrogen in an uninterrupted manner into the blood stream through the skin. Contraception is also achieved through depot specific injections. For instance, Depo provera is medroxyprogesterone acetate which could ... Read More
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