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Hypercoagulable State - Assignment Example

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This paper will discuss how to bridge the patient (Amanda) from warfarin for cholecystectomy surgery as per the surgical bleeding risk. Amanda was at a pre-procedure INR of 2.2; therefore, warfarin…
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Hypercoagulable State
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Hypercoagulable State

This medication is Dalteparin Sodium 5000 IU o.d. The reason I chose this medication and not others is because this medication minimizes the time that patients are not therapeutically anticoagulated, thus reduces the risk of thromboembolism (Leizorovicz et al., 2004). Moreover, a fixed low dose rate of LWMH has proved to be reliable as compared to the other classes of medication. This is because it diminishes the chances of thrombotic complications (Erkens & Prins, 2010).
Adverse drug reactions include bleeding at any site, pain and reactions at the injection site, hair loss, haematoma, and type 1 thrombocytopenia. These side effects can be managed by alerting any medical attendant so that they give the correct management guidelines. However, these side effects go away on their own after some time (Bick, 2002). Worst case scenarios include bleeding from the injection site, allergic reaction signs (swelling of the lips, face, tongue, rash, difficulty in breathing), nose bleeding, bloody stools, increased menstrual bleeding, and signs of stroke. If the mentioned worst case scenarios happen, then the patient must stop taking the medication immediately medical attention immediately.
Several drugs have been known to interact with Dalteparin i.e. platelet inhibitors, oral anticoagulants, and thrombolytics. The combination of Dalteparin with these drugs has shown that the risk outweighs the benefit. I.e. severe bleeding may be seen when the drug is combined with other blood thinning agents and anticoagulants, Dalteparin has been known to increase potassium levels when combined with ACE inhibitors. Combinations have to avoid with Dalteparin unless under special circumstances. An applicable measure for this patient is not combining Dalteparin with any other medication (Burton, 2005).
I prescribed a generic name. No, there is no available generic version for this medication. The brand name for the medication ... Read More
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