The best known NSAID, is the original and oldest, aspirin, in use since the last century before the Food and Drug Administration (FDA) was formed. For this reason aspirin has always been an over-the-counter drug. The other NSAIDs are prescription drugs except ibuprofen (Advil, Nuprin, and others), ketoprofen (Orudis KT, Actron), and naproxen (Aleve). Other NSAIDs must be approved by the FDA for use in people with arthritis. Acetaminophen (Tylenol and others) is considered a painkiller only and is also sold over the counter. The NSAID group includes aspirin, ibuprofen (marketed under the names Motrin and Advil) and naproxen (Aleve). It does not include acetaminophen (Tylenol), which is effective against pain and fever but not against inflammation - which is a major factor in certain types of pain, such as the ache of rheumatoid arthritis.
The search for the journals was done using the most trusted websites such as the yahoo and google. Upon entering the website I was able to access the MEDLINE and Cochrane website. Several studies were presented during my research, but the focus of the study is to evaluate the systematic review done by journals. Here I found a relevant study for the effectiveness of the NSAID in gastric ulcer or stomach cancer. systematic review of the relationship of the NSAID with gastric cancer can be found in MEDLINE. A strategy of research was done to show the risk rate of the NSAID. Using the following database, Cochrane, EMBASE and MEDLINE, the systematic review shows that the use of NSAID in pain with gastric cancer can be helpful in a dose dependent manner. Continuing the search on these databases I was able to prove that the study done by Wang on the effect of NSAID in gastric ulcer can be proven. ...
wing database, Cochrane, EMBASE and MEDLINE, the systematic review shows that the use of NSAID in pain with gastric cancer can be helpful in a dose dependent manner. Continuing the search on these databases I was able to prove that the study done by Wang on the effect of NSAID in gastric ulcer can be proven. Continuing my research for the effectiveness of NSAID, I was able to open the website showing the systematic review using the database of MEDLINE, Pubmed, and Cancerlit. The said study can be found in the Oxford journals. To easily compare the result of the two reviews, the results, sources and analysis were put into a table. The conclusion of the study was based on the review done by the authors using the journal's databases.
Keywords: NSAIDs, systematic review, effectiveness and gastric cancer
Systematic Review of Journals
This systematic review was being studied by Wei Hong Wang, Jia Qing Huang, Ge Fan Zheng, Shiu Kum Lam, Johan Karlberg, Benjamin Chun-Yu Wong. Background: The authors of this review was able to identify the relationship between the use of non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin, and the risk of gastric cancer. They performed a systematic review and meta-analysis of published studies to evaluate the association between use of this class of drugs and the risk of gastric cancer. The results and methods are being showed in the table below. The conclusion of this study shows that NSAID use was associated with a decreased risk of gastric cancer in a dose-dependent manner. This finding warrants proper clinical trials in populations with high risk of gastric cancer. The author developed the search strategy in MEDLINE and modified it for other databases. The search was limited to English-language reports of