Hemophilia is an X-linked hereditary disorder. The disease is characterized by spontaneous or injury-related bleeding. Hemophilia comes in two types, A and B. Both types are the result of gene defects. Hemophilia A is a deficiency of factor VIII occurring in 1 in 10,000 people while Hemophilia B is a deficiency of factor IX occurring in 1 in 40,000.
The oral condition of the human being is characterized by episodes of tooth loss and damage of the gums which leads to bleeding. Keeping the gums and the teeth healthy usually requires procedures that are invasive ( prone to injury). One can just imagine the gravity of the situation to people with hemophilia. That is why one can find numerous studies and researches about the
People with hemophilia or congenital bleeding tendencies are a priority group for dental and oral health care, since bleeding after dental treatment may cause severe or even fatal complications. Maintenance of a healthy mouth and prevention of dental problems is of great importance, not only to quality of life and nutrition but also to avoid the dangers of surgery. .
Plaque accumulation causes inflammation of the gums (gingivitis) due to the action of bacteria. This may progress to the damage of the attachment of the teeth to the jawbone (periodontal membrane) resulting to inflammation and damage to this membrane (chronic periodontitis). Ultimately, this leads to the loosening of a tooth and then tooth loss. With the plaque allowed to calcify, tartar develops above and/or below the gum-line making further accretion of plaque result to Fig 2. The Parts of A Tooth
Gingivitis is painless but leads to the ...
Thru the process of prophylaxis or cleaning of the teeth and gums by the doctor, gingivitis can be prevented thereby limiting bleeding of the gums and eliminating the need for surgery. This can be seen as a pro-active step rather than waiting for the gums to bleed and make use of factor concentrates to stop the bleeding.
The treatment of hemophilia has been undergoing significant innovations since the development of factor VIII concentrates. The current trend of thinking is that prophylaxis is a beneficial therapy for patients with hemophilia A as compared to on-demand treatment. The observed benefits include reduced number of bleeding episodes, improved joint function and a relatively healthier patient. Hoots et al reviewed the literature about the topic and weighed the value of these benefits against the increased expense due to increased factor use. (Hoots et al, 2006)
How Is Dental Surgery Performed To A Hemophiliac
Performing dental surgery on a hemophiliac patient, even for a simple dental extraction, must be thoroughly planned such that the risk of bleeding, hematoma formation or excessive bruising is minimized. To prevent any problems or complications, the two following points must be realized:
Rarely will emergency dental surgical intervention be required as control of pain can be registered without resorting to an unplanned treatment.
Discussions with Hemophilia patients requiring prophylactic cover concerning the treatment plans must be done
For those suffering from severe hemophilia, factor replacement is a necessary pre-surgery procedure along with regional block injections or scaling. Those suffering from hemophilia A usually require a dose of 50 iu/kg of factor VIII and a dose of 100 iu/kg of factor IX in hemophilia ...
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(Hemophilia Disease Essay Example | Topics and Well Written Essays - 1250 Words)
“Hemophilia Disease Essay Example | Topics and Well Written Essays - 1250 Words”, n.d. https://studentshare.net/miscellaneous/282126-hemophilia-disease.
Functionally, it synthesizes substances of almost all clotting factors necessary in coagulation process. Meanwhile, vitamin K, which is synthesized in the intestine by bacteria, is also necessary for hepatic synthesis of prothrombin, serum prothrombin conversion accelerator or factor VII, plasma thromboplastin component or factor IX, factor X, and protein C.
Petersburg”2. Even after hundreds of years from his death, the controversies surrounding him still remain unanswered. Although he was a self declared saint, his teachings were not the same as the teachings of other normal saints or the teachings of the religions.
Carrying out various tests to establish the presence of the disease is very essential. This is because bleeding may occur due to other conditions other than Hemophilia A. In addition, tests are important to distinguish the disease from other forms of Hemophilia.
The term “software as a service” or commonly known as ‘SaaS’ is used to describe the process within which software is delivered to the end users over the internet and does not require any locally managed servers or applications. The business houses providing such services either charges from the end user as an on-going fee or can even use advertisements to pay for the services (Ryder, 2009).
In many instances, the outbreaks have severely strained both the local and national resources during periods when health care expenditure in the economically developed states has been restrained. Emerging illness is a phrase that has been utilized with augmenting occurrence to delineate the appearance of an unidentified contagion, or a beforehand identified contagion that expanded to a new ecological niche or a geographical area (Howard & Fletcher, 2012).
Whenever such movements of stomach acids likes the hydrochloric acid that help in the digestion of food leaks from the stomach back to the esophagus, the mucus lining of the wall prevent them from corroding the esophagus. Additionally, such backward movement of stomach and intestinal acids are rare since the digestion system has a mechanism of enclosing both the stomach and the intestines thus preventing such occurrences.
It is a recessive disease which results due to the lack of clotting factors VIII and IX. This can be explained as the genes for both of these factors are present on the X chromosome (Tomlinson 2005; VanPutte et al 2011).
For a female to
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