Chemotherapy: High-Risk Complications

Chemotherapy: High-Risk Complications Research Paper example
College
Research Paper
Nursing
Pages 4 (1004 words)
Download 0
Chemotherapy: High Risk Complications Wesling Ducos Advanced Med-Surg 6-26-12 Chemotherapy: High Risk Complications Introduction In chemotherapy treatment, the drugs used to cure cancer can have a number of high risk complications including adverse reactions and toxicities…

Introduction

Chemotherapy-related Nephrotoxicity Studies indicate that chemotherapeutic drugs may damage glomerulus, renal tubules, or microvasculature and thereby lead to renal problems. Adverse reactions can be mild or fatal. Some commonly used nephrotoxic antineoplastic agents like Cisplatin may develop proximal and distal tubule damages. The injury level may vary in accordance with the dosage. High dose cisplatin therapy would result in acute tubular necrosis, which is a condition limiting tubules’ sodium, magnesium, and water reabsorption capabilities. This condition in turn may lead to chronic electrolyte abnormalities too. “Even when aggressive pre and posthydration with mannitol induced diuresis are part of the cisplatin regimen, the patient may develop nephrotoxicity” (Held-Warmkessel, 2011) In order to reduce those risks, it is necessary to closely monitor renal activities following the drug administration. Similarly, methotrexate causes damage to renal tubules and collecting ducts and ultimately results in acute tubular necrosis. While giving high dose therapy, drug precipitates out of the solution and is accumulated in tubules ducts; this condition may worsen the injury. Acute kidney injury is more likely to occur at any time during this treatment. ...
Download paper
Not exactly what you need?

Related papers

Dietary Education Program for Patients at High Risk of Coronary Heart Disease
Conclusion and Recommendations P. 47 – P. 50 10. References P. 51 – P. 55 11. Bibliography P. 56 12. Appendices P. 65-83 Tables Table 1 Boolean Table P. 22-23 Table 2 Search Terms Acknowledgement My sincere thanks to people who have helped in the formulation of this paper, from the initial typing of the draft to the editing and correction my heart is filled with thanks. To my supervisor who…
Neutropenia in the chemotherapy patient
The concerns that come from this are numerous. Firstly, chemotherapy is a stressful time for the human body, and therefore any further weakening such as neutropenia can cause severe distress and further illness to the patient (Schwenkglenks, 2011). Secondly, as the primary role of neutrophils is to prevent against infection and cancer patients have multiple and frequent contact with the hospital…
Neutropenia in the Chemotherapy Patient
The study by Cameron (2009) suggests that one of the most effective ways of lowering the incidence of mortality from neutropenia is educating the patients. The paper suggests that letting the patients know what the signs of (febrile) neutropenia are and how they can be recognized will allow patients to understand when to contact their healthcare provider to ensure that they receive treatment for…
Decreasing Rates of Neutropenia in the Chemotherapy Patient
This paper will identify the evidence for the change in practice and then outline a method to implement the project using Rosswurm and Larrabee’s model for evidence-based change (Rosswurm & Larrabee, 1999). Finally, a measurable plan for evaluating the success of the evidence-based change will be outlined to ensure that the results are living up to the expectations outlined by the evidence.…
Approcah to Care - Breast Cancer
Etiology of Breast Cancer Breast cancer is the most common kind of cancer that is prevalent among women in U.S. It is estimated that about 192,000 new cases of breast cancer are found in U.S. alone each year. Substantial clinical evidence suggests that hormones play a critical role in the etiology of various cancers and breast cancer is one of them. Estrogen is the chief stimulant in proliferation…
HIgh Risk Families
(2011), pregnancy can develop problem behaviours and increased substance use in teen around 14years of age. This is because of the confounding effect of variables, such as maternal socio-demographic status, mental health and substance use during pregnancy (p.200). During pregnancy, a female undergoes many psychological changes or mood changes. Even matured females are sometimes face problems in…
Evidence Based Article
The authors point that the use of the Chemotherapy-induced neutropenia has caused delays and reductions in patients with early stages of breast cancer and has compromised the treatment outcomes especially with treatable tumors. The authors also state that febrile neutropenia (FN) has shown a high risk for serious complications in cancer patients and requires quick medical intervention for cancer…