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Meter Dose Inhaler verses Nebulizer Treatment
Pages 3 (753 words)
PICO Assignment Clinical question P- Pediatric age group patients with acute wheezing I- Albuterol administration using metered dose inhaler C-Albuterol administration using nebuliser O- Resolution of symptoms and side effects What event generated the clinical question?
Patients frequently ask health care providers as to which is a better mode of administration in terms of efficacy, convenience and safety. This triggered me to find evidence to ascertain as to which of the two is a better mode of administration in acute wheezing. Thus, it was both problem focused and knowledge focused trigger that generated the clinical question. Names/Types of research sources used The research source used was PubMed. Summation of the research findings as related to the clinical question Rodrigo and Rodrigo (1998) performed a randomized, double-blind, parallel-group study to compare the efficacy of salbutamol (or albuterol) delivered by either metered-dose inhaler plus spacer (MDI-spacer) or by nebulization, and to determine the relationships between physiologic responses and plasma salbutamol concentrations. The study revealed that bronchodilatation remained same with metered dose inhalation and nebulization, but side effects were more with nebulization because of higher levels of plasma salbutamol due to increased absorption. Deerajanawong et al (2005) conducted a prospective randomized, double-blind, placebo-controlled trial with an aim to compare the efficacy of salbutamol aerosol therapy given metered dose inhaler and nebulization in young children with acute wheezing. ...
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