literature review

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LITERATURE REVIEW: SLEEP APNEA TREATMENT TRIALS Abstract Sleep apnea is a sleeping disorder characterized by the cessation of airflow in the airways (apnea) and a reduction of oxygen intake by 50% and above (hypopnea) for 10 seconds or more per hour during sleep.


Based on various reports, it is suggested that in any kind of treatment for sleep apnea, a strict adherence to treatment methods is the key for prolonged AHI reduction among patients. Literature Review: Sleep Apnea Treatment Trials Sleep apnea is defined as the cessation of airflow through the nose or mouth for at least 10 seconds every sleeping hour, which decreases at least 3% oxyhemoglobin in the blood and a reduction of 50% in oxygen intake among patients (Noseda, et al., 2004). The total of apnea (due to obstruction) and hypopnea (airflow reduction) events during sleep is measured as the apnea-hypopnea index (AHI), and the number is positively correlated to the severity of sleep apnea. Possible causes are multifactorial, ranging from abnormal cranial structures, relaxed airway muscles or problems with respiratory control during sleep (Barnes, et al., 2009). Effects can range from excessive daytime sleepiness, dysfunction in the patient’s metabolism and neurocognition, cardiovascular disorders, and mood swings with a decreased quality of life (Ackel-D’Elia, et al., 2012; Kline, et al., 2012; Quan, et al., 2007). ...
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